Abstract P-glycoprotein (P-gp) is an ATP-dependent efflux pump encoded by the MDR1
gene in humans, known to mediate multidrug resistance of neoplastic cells to cancer …

The MYC transcription factor, encoded by the c‐MYC proto‐oncogene, is activated by
growth‐promoting signals, and is a key regulator of biosynthetic and metabolic pathways …

Using the DNA origami technique, we constructed a DNA nanodevice functionalized with
small interfering RNA (siRNA) within its inner cavity and the chemotherapeutic drug …

All successful cancer therapies are limited by the development of drug resistance. The
increase in the understanding of the molecular and biochemical bases of drug efficacy has …

Flavonoids, including isoflavones, are natural components in our diet and, with the
burgeoning interest in alternative medicine, are increasingly being ingested by the general …

In recent years, there has been an increased understanding of P-glycoprotein (P-GP)-
mediated pharmacokinetic interactions. In addition, its role in modifying the bioavailability of …

Simple Summary Osteosarcoma (OS), the most common primary bone tumor, mainly affects
children and adolescents. Unfortunately, in some cases, the absence of response to …

-jie Chen: Janice E. Chin: Kazumitsu Ueda, t las P. Clark, t $ Ira Pastan, t el M. Gottesman,?
and lgor B. Roninson” er for Genetics Iversity of Illinois College of Medicine at Chicago …

Multidrug resistance (MDR) is a major obstacle in the clinical treatment of cancer. Herein, a
facile strategy is reported to construct a versatile DNA nanostructure as a co‐delivery vector …

The presented review is an attempt to summarize a huge volume of data on 5-ene-4-
thiazolidinones being a widely studied class of small molecules used in modern organic and …