Recent progress in metal-organic cages for biomedical application: Highlighted research during 2018–2023

YP Wang, Y Zhang, XH Duan, JJ Mao, M Pan… - Coordination Chemistry …, 2024 - Elsevier
Metal-organic cages (MOCs) are a class of widely used nanosize supramolecular
architectures with specific geometric shapes and confined cavities, constructed from the …

DNA hydrogels and nanogels for diagnostics, therapeutics, and theragnostics of various cancers

I Zare, R Taheri-Ledari, F Esmailzadeh, MM Salehi… - Nanoscale, 2023 - pubs.rsc.org
As an efficient class of hydrogel-based therapeutic drug delivery systems, deoxyribonucleic
acid (DNA) hydrogels (particularly DNA nanogels) have attracted massive attention in the …

DNA supramolecular hydrogel-enabled sustained delivery of metformin for relieving osteoarthritis

C Zhang, H Huang, J Chen, T Zuo, Q Ou… - … Applied Materials & …, 2023 - ACS Publications
Osteoarthritis (OA) is a musculoskeletal disorder affecting∼ 500 million people worldwide.
Metformin (MET), as an oral hypoglycemic drug approved by the Food and Drug …

Construction of an Injectable Composite Double-Network Hydrogel as a Liquid Embolic Agent

S Ai, Q Gao, G Cheng, P Zhong, P Cheng… - …, 2024 - ACS Publications
Conventional embolists disreputably tend to recanalization arising from the low filling ratio
due to their rigidity or instability. As a result, intelligent hydrogels with a tunable modulus …

Intelligent DNA-Based Hydrogels for Bioanalysis and Therapeutics

Q Zhu, C Shen, R Chen, C Mao, Y He… - ACS Applied Polymer …, 2023 - ACS Publications
DNA is a type of biomacromolecule that can be modified and designed through enzymatic or
chemical techniques, and it serves as both a biological reactive entity and a polymer. In …

An injectable, in situ forming and NIR-responsive hydrogel persistently reshaping tumor microenvironment for efficient melanoma therapy

H Zhang, L Hu, W Xiao, Y Su, D Cao - Biomaterials Research, 2023 - spj.science.org
Background Melanoma is a highly aggressive form of skin cancer with increasing incidence
and mortality rates. Chemotherapy, the primary treatment for melanoma, is limited by …

Advances in Intelligent Stimuli‐Responsive Microneedle for Biomedical Applications

K Xu, J Weng, J Li, X Chen - Macromolecular Bioscience, 2023 - Wiley Online Library
Microneedles (MNs) are a new type of drug delivery method that can be regarded as an
alternative to traditional transdermal drug delivery systems. Recently, MNs have attracted …

Recent advances in DNA-based probes for Photoacoustic Imaging

A Anil, J Chaskar, AB Pawar, A Tiwari… - Journal of Biotechnology, 2024 - Elsevier
Photoacoustic imaging (PAI) is a widely developing imaging modality that has seen
tremendous evolvement in the last decade. PAI has gained the upper hand in the imaging …

Advanced Applications of DNA Hydrogels in Fluorescence Sensing

Z Ma, S Tang, W Shen, HK Lee - TrAC Trends in Analytical Chemistry, 2024 - Elsevier
In recent years, DNA hydrogels have attracted widespread attention in the field of
fluorescence detection due to their high sensitivity and lower biotoxicity, providing new tools …

DNA Hydrogels with Programmable Condensation, Expansion, and Degradation for Molecular Carriers

K Jeon, C Lee, JY Lee, DN Kim - ACS Applied Materials & …, 2024 - ACS Publications
Molecular carriers are necessary for the controlled release of drugs and genes to achieve
the desired therapeutic outcomes. DNA hydrogels can be a promising candidate in this …