Immersed boundary methods for simulating fluid–structure interaction

F Sotiropoulos, X Yang - Progress in Aerospace Sciences, 2014 - Elsevier
Fluid–structure interaction (FSI) problems commonly encountered in engineering and
biological applications involve geometrically complex flexible or rigid bodies undergoing …

Fluid mechanics of heart valves and their replacements

F Sotiropoulos, TB Le, A Gilmanov - Annual Review of Fluid …, 2016 - annualreviews.org
As the pulsatile cardiac blood flow drives the heart valve leaflets to open and close, the flow
in the vicinity of the valve resembles a pulsed jet through a nonaxisymmetric orifice with a …

Fluid–structure interaction of an aortic heart valve prosthesis driven by an animated anatomic left ventricle

TB Le, F Sotiropoulos - Journal of computational physics, 2013 - Elsevier
We develop a novel large-scale kinematic model for animating the left ventricle (LV) wall
and use this model to drive the fluid–structure interaction (FSI) between the ensuing blood …

Finite-span rotating wings: three-dimensional vortex formation and variations with aspect ratio

ZR Carr, C Chen, MJ Ringuette - Experiments in fluids, 2013 - Springer
We investigate experimentally the effect of aspect ratio () on the time-varying, three-
dimensional flow structure of flat-plate wings rotating from rest at 45° angle of attack. Plates …

On the three-dimensional vortical structure of early diastolic flow in a patient-specific left ventricle

TB Le, F Sotiropoulos - European Journal of Mechanics-B/Fluids, 2012 - Elsevier
We study the formation of the mitral vortex ring during early diastolic filling in a patient-
specific left ventricle using direct numerical simulation. The geometry of the left ventricle is …

On the flow structure of an inclined jet in crossflow at low velocity ratios

C Dai, L Jia, J Zhang, Z Shu, J Mi - International Journal of Heat and Fluid …, 2016 - Elsevier
This study investigates the influence of different low velocity ratios on the flow structures of
an inclined jet in crossflow (JICF). Experiments are conducted in a closed-loop water tunnel …

Effects of a nozzle on the propeller wake in an oblique flow using modal analysis

T Wang, H Shi, M Zhao, Q Zhang - Journal of Fluid Mechanics, 2023 - cambridge.org
The effect of a nozzle on the wake dynamics of a four-bladed propeller operating in an
oblique flow is investigated via modal decomposition and flow visualization of the results …

Computational methods for fluid-structure interaction simulation of heart valves in patient-specific left heart anatomies

TB Le, M Usta, C Aidun, A Yoganathan, F Sotiropoulos - Fluids, 2022 - mdpi.com
Given the complexity of human left heart anatomy and valvular structures, the fluid–structure
interaction (FSI) simulation of native and prosthetic valves poses a significant challenge for …

Three-dimensional flow visualization in the wake of a miniature axial-flow hydrokinetic turbine

LP Chamorro, DR Troolin, SJ Lee, REA Arndt… - Experiments in …, 2013 - Springer
Three-dimensional 3-component velocity measurements were made in the near wake
region of a miniature 3-blade axial-flow turbine within a turbulent boundary layer. The model …

Vortex phenomena in sidewall aneurysm hemodynamics: experiment and numerical simulation

TB Le, DR Troolin, D Amatya, EK Longmire… - Annals of biomedical …, 2013 - Springer
We carry out high-resolution laboratory experiments and numerical simulations to
investigate the dynamics of unsteady vortex formation across the neck of an anatomic in vitro …