A timely review of cross-kingdom regulation of plant-derived MicroRNAs

D Li, J Yang, Y Yang, J Liu, H Li, R Li, C Cao… - Frontiers in …, 2021 - frontiersin.org
MicroRNAs (miRNAs) belong to a class of non-coding RNAs that suppress gene expression
by complementary oligonucleotide binding to the sites in target messenger RNAs …

Plant extracellular vesicles: A novel bioactive nanoparticle for tumor therapy

ZL Tan, JF Li, HM Luo, YY Liu, Y Jin - Frontiers in Pharmacology, 2022 - frontiersin.org
Extracellular vesicles are tiny lipid bilayer-enclosed membrane particles, including apoptotic
bodies, micro vesicles, and exosomes. Organisms of all life forms can secrete extracellular …

Antioxidant Phytocomplexes Extracted from Pomegranate (Punica granatum L.) Using Hydrodynamic Cavitation Show Potential Anticancer Activity In Vitro

A Minutolo, A Gismondi, R Chirico, G Di Marco… - Antioxidants, 2023 - mdpi.com
Hydrodynamic cavitation (HC), as an effective, efficient, and scalable extraction technique
for natural products, could enable the affordable production of valuable antioxidant extracts …

Effect of microvesicles from Moringa oleifera containing miRNA on proliferation and apoptosis in tumor cell lines

M Potestà, V Roglia, M Fanelli, E Pietrobono… - Cell death …, 2020 - nature.com
Human microvesicles are key mediators of cell–cell communication. Exosomes function as
microRNA transporters, playing a crucial role in physiological and pathological processes …

[HTML][HTML] Nutri-epigenetic effects of phenolic compounds from extra virgin olive oil: a systematic review

A del Saz-Lara, MCL de Las Hazas, F Visioli… - Advances in …, 2022 - Elsevier
Dietary components can induce epigenetic changes through DNA methylation, histone
modification, and regulation of microRNAs (miRNAs). Studies of diet-induced epigenetic …

Dietary microRNAs and cancer: A new therapeutic approach?

A Dávalos, L Pinilla, MCL de Las Hazas… - Seminars in Cancer …, 2021 - Elsevier
Cancer is one of the leading causes of premature death and constitutes a challenge for both
low-and high-income societies. Previous evidence supports a close association between …

Looking for plant microRNAs in human blood samples: bioinformatics evidence and perspectives

L Olmi, G Pepe, M Helmer-Citterich, A Canini… - Plant Foods for Human …, 2023 - Springer
Literature has proposed the existence of a cross kingdom regulation (CRK) between human
and plants. In this context, microRNAs present in edible plants would be acquired through …

Plant miRNAs reduce cancer cell proliferation by targeting MALAT1 and NEAT1: a beneficial cross-kingdom interaction

F Marzano, MF Caratozzolo, A Consiglio… - Frontiers in …, 2020 - frontiersin.org
MicroRNAs (miRNAs) are ubiquitous regulators of gene expression, evolutionarily
conserved in plants and mammals. In recent years, although a growing number of papers …

Plant miR171 modulates mTOR pathway in HEK293 cells by targeting GNA12

A Gismondi, V Nanni, V Monteleone, C Colao… - Molecular biology …, 2021 - Springer
Plant microRNAs have shown the capacity to regulate mammalian systems. The potential
bioactivity of miR171vr, an isoform of the plant miR171, on human embryonic kidney 293 …

Exogenous miRNAs from Moringa oleifera Lam. recover a dysregulated lipid metabolism

V Roglia, M Potestà, A Minchella, SP Bruno… - Frontiers in Molecular …, 2022 - frontiersin.org
A balanced diet is critical for human health, and edible plants play an important role in
providing essential micronutrients as well as specific microRNAs (miRNAs) that can regulate …