The aim of this review was to (i) acknowledge structural advantages of natural products
(NPs) for designing therapeutic drugs;(ii) emphasize how wildlife conservation is socially …

The skin of the toad Bufo bufo gargarizans Cantor is known to be rich in bufadienolides,
peptides and alkaloids. It has been found to be a source of some extracts and biologically …

Covering: 1998 to July 2010 Since 1998, a great number of bufadienolides have been
reported from plants, animals and plant cell suspensions, as well as from fungi and bacteria …

Ethnopharmacological relevance Among amphibians, 15 of the 47 species reported to be
used in traditional medicines belong to the family Bufonidae, which demonstrates their …

Toxins from toads have long been known to contain rich chemicals with great
pharmaceutical potential. Recent studies have shown more than 100 such chemical …

Amphibians present pharmacologically active aliphatic, aromatic and heterocyclic molecules
in their skin as defense against microorganisms, predators and infections, such as steroids …

Marinobufagenin (MBG) is a member of the bufadienolide family of compounds, which are
natural cardiac glycosides found in a variety of animal species, including man, which have …

The venom of amphibians is a fascinating source of active substances. In view of their
medical importance and aiming to explore the amazing Brazilian biodiversity, we conducted …

A large proportion of cancer patients fail to respond to conventional chemotherapy because
of the intrinsic resistance of their cancer to pro-apoptotic stimuli and/or the acquisition of a …

The cardiac glycosides are a group of compounds isolated from plants and some animals.
They have been used in therapy for heart failure for many years. The cytotoxic effect of many …