Light based anti-infectives: ultraviolet C irradiation, photodynamic therapy, blue light, and beyond
Highlights•Light-based anti-infectives work against biofilms and localized
infections.•Ultraviolet C light will kill all pathogens without killing host mammalian …
infections.•Ultraviolet C light will kill all pathogens without killing host mammalian …
[HTML][HTML] Syrian hamster as an animal model for the study on infectious diseases
J Miao, LS Chard, Z Wang, Y Wang - Frontiers in immunology, 2019 - frontiersin.org
Infectious diseases still remain one of the biggest challenges for human health. In order to
gain a better understanding of the pathogenesis of infectious diseases and develop effective …
gain a better understanding of the pathogenesis of infectious diseases and develop effective …
Carbaporphyrinoid systems
TD Lash - Chemical reviews, 2017 - ACS Publications
Following immediately after the serendipitous discovery of N-confused porphyrins,
remarkably diverse carbaporphyrinoid systems have been synthesized and investigated. By …
remarkably diverse carbaporphyrinoid systems have been synthesized and investigated. By …
Synthesis of novel quinoline–based 4, 5–dihydro–1H–pyrazoles as potential anticancer, antifungal, antibacterial and antiprotozoal agents
J Ramírez–Prada, SM Robledo, ID Vélez… - European journal of …, 2017 - Elsevier
A new series of N–substituted 2–pyrazolines 9a–f, 10a–f, 11a–f, 12a–f and 13a–f were
obtained from the cyclocondensation reaction of [(7–chloroquinolin–4–yl) amino] chalcones …
obtained from the cyclocondensation reaction of [(7–chloroquinolin–4–yl) amino] chalcones …
[HTML][HTML] Pheophorbide a: State of the Art
Chlorophyll breakdown products are usually studied for their antioxidant and anti-
inflammatory activities. The chlorophyll derivative Pheophorbide a (PPB a) is a …
inflammatory activities. The chlorophyll derivative Pheophorbide a (PPB a) is a …
Phototherapy and optical waveguides for the treatment of infection
With rapid emergence of multi-drug resistant microbes, it is imperative to seek alternative
means for infection control. Optical waveguides are an auspicious delivery method for …
means for infection control. Optical waveguides are an auspicious delivery method for …
Synthesis, leishmanicidal, trypanocidal and cytotoxic activities of quinoline-chalcone and quinoline-chromone hybrids
JC Coa, E García, M Carda, R Agut, ID Vélez… - Medicinal Chemistry …, 2017 - Springer
We report herein the synthesis and biological activities (cytotoxicity, leishmanicidal and
trypanocidal) of six quinoline-chalcone and five quinoline-chromone hybrids. The …
trypanocidal) of six quinoline-chalcone and five quinoline-chromone hybrids. The …
An efficient synthesis of new caffeine-based chalcones, pyrazolines and pyrazolo [3, 4-b][1, 4] diazepines as potential antimalarial, antitrypanosomal and …
A new series of chalcones 5a–f were synthesized from caffeine-based aldehyde 3 and
substituted acetophenones 4a–f. Treatment of compounds 5a–f with hydrazine hydrate led …
substituted acetophenones 4a–f. Treatment of compounds 5a–f with hydrazine hydrate led …
Liposomal drug delivery systems for the treatment of leishmaniasis
Human le ishmaniasis is a vector-borne, neglected infectious disease that is widely
distributed in America, Africa, Europe, and Asia. Current therapy is based on old and toxic …
distributed in America, Africa, Europe, and Asia. Current therapy is based on old and toxic …
Current status of liposomal porphyrinoid photosensitizers
P Skupin-Mrugalska, J Piskorz, T Goslinski… - Drug discovery today, 2013 - Elsevier
Highlights•Liposomes as highly potent carriers for porphyrinoid photosensitizer
delivery.•Visudyne®–the first commercially available liposomal photosensitizer.• …
delivery.•Visudyne®–the first commercially available liposomal photosensitizer.• …