There is an urgent need to develop safer and more effective modalities for the treatment of a
wide range of pathologies due to the increasing rates of drug resistance, undesired side …

One of the most effective therapeutic decencies in the treatment of Type 2 Diabetes Mellitus
is the inhibition of α-glucosidase enzyme, which is present at the brush border of the …

The synthesis of eleven new and previously undescribed benzamides was designed. These
compounds were specifically projected as potential inhibitors of the enzymes …

Neurodegenerative disorders (NDs) include a large range of diseases characterized by
neural dysfunction with a multifactorial etiology. The most common NDs are Alzheimer's …

Aims Type 1 diabetes mellitus (T1DM) is associated with increased risk of cardiovascular
disease (CVD) and mortality. The underlying mechanisms for T1DM-induced heart disease …

In the current study, a series of fluorine-substituted piperidine derivatives (1–8) has been
synthesized and characterized by various spectroscopic techniques. In vitro and in vivo …

Aim: A new series of 1, 2, 3-triazole-hydrazone derivatives were developed to evaluate their
anti-Alzheimer's activity. Materials & methods: All compounds were screened toward …

Abstract A series of coumarin‐1, 3, 5‐triazine derivatives were designed, synthesized and
evaluated as acetylcholinesterase inhibitors. The structures of those compounds were …