Aminoacyl-tRNA synthetases (ARSs) are universal enzymes that catalyze the attachment of
amino acids to the 3′ ends of their cognate tRNAs. The resulting aminoacylated tRNAs are …

The mangrove ecosystem is considered as an attractive biodiversity hotspot that is
intensively studied in the hope of discovering new useful chemical scaffolds, including those …

Covering: up to the second quarter of 2020 Threat or treat? While pathogenic bacteria pose
significant threats, they also represent a huge reservoir of potential pharmaceuticals to treat …

The unfolded protein response (UPR) is an integrated, adaptive biochemical process that is
inextricably linked with cell homeostasis and paramount to maintenance of normal …

Background: Resistance to therapy is a major hindrance to patient survival in cancer,
underscoring a critical need to elucidate the underlying mechanisms responsible for …

Despite advances in cancer therapy, several persistent issues remain. These include cancer
recurrence, effective targeting of aggressive or therapy-resistant cancers, and selective …

Biopesticides are an attractive biotechnological alternative to conventional pesticides for soil-
borne plant diseases. A screening strategy with over 100 actinomycetes bacteria isolated …

In neurological disorders, both acute and chronic neural stress can disrupt cellular
proteostasis, resulting in the generation of pathological protein. However in most cases …

A paucity of advances in the development of novel therapeutic agents for squamous cell
carcinomas of the head and neck, oral cavity (OSCC) and oropharynx, has stagnated …

Spiroimines are a class of compounds produced by marine dinoflagellates with a wide
range of toxicity and therapeutic potential. The smallest of the cyclic imines, portimine, is far …