Protein arginine methyltransferase (PRMT)-mediated arginine methylation is an important
post-transcriptional modification that regulates various cellular processes including …

Stress granule formation is triggered by the release of mRNAs from polysomes and is
promoted by the action of the RNA-binding proteins G3BP1/2. Stress granules have been …

Viruses interact with numerous host factors to facilitate viral replication and to dampen
antiviral defense mechanisms. We currently have a limited mechanistic understanding of …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a positive single-stranded
RNA virus, engages in complex interactions with host cell proteins throughout its life cycle …

Several biomolecular condensates assemble in mammalian cells in response to viral
infection. The most studied of these are stress granules (SGs), which have been proposed to …

G3BP1 is an RNA binding protein that condenses untranslating messenger RNAs into stress
granules (SGs). G3BP1 is inactivated by multiple viruses and is thought to antagonize viral …

Zika virus (ZIKV) has become a global health problem over the past decade due to the
extension of the geographic distribution of the Asian/American genotype. Recent epidemics …

Viruses deploy multiple strategies to suppress the host innate immune response to facilitate
viral replication and pathogenesis. Typical G3BP1+ stress granules (SGs) are usually …

Viruses interact with numerous host factors to facilitate viral replication and to dampen
antiviral defense mechanisms. We currently have a limited mechanistic understanding of …

Proper transcription regulation by key transcription factors, such as IRF3, is critical for anti-
viral defense. Dynamics of enhancer activity play important roles in many biological …