Natural and synthetic flavonoid derivatives as new potential tyrosinase inhibitors: A systematic review

RJ Obaid, EU Mughal, N Naeem, A Sadiq… - RSC …, 2021 - pubs.rsc.org
Tyrosinase is a multifunctional glycosylated and copper-containing oxidase that is highly
prevalent in plants and animals and plays a pivotal role in catalyzing the two key steps of …

Cold plasma interactions with enzymes in foods and model systems

NN Misra, SK Pankaj, A Segat, K Ishikawa - Trends in Food Science & …, 2016 - Elsevier
Background The past decade has seen an increased interest in the application of non-
equilibrium plasma for food processing. An important aspect of the interaction of chemical …

Synthesis, antioxidant and anti-tyrosinase activity of 1, 2, 4-triazole hydrazones as antibrowning agents

Z Peng, G Wang, QH Zeng, Y Li, Y Wu, H Liu, JJ Wang… - Food Chemistry, 2021 - Elsevier
Abstract A series of 1, 2, 4-triazole hydrazones (1–16) were synthesized, and their inhibitory
activities and mechanisms on tyrosinase were investigated by ultraviolet spectrophotometry …

Natural and bioinspired phenolic compounds as tyrosinase inhibitors for the treatment of skin hyperpigmentation: Recent advances

L Panzella, A Napolitano - Cosmetics, 2019 - mdpi.com
One of the most common approaches for control of skin pigmentation involves the inhibition
of tyrosinase, a copper-containing enzyme which catalyzes the key steps of melanogenesis …

Chemistry and biochemistry of cold physical plasma derived reactive species in liquids

K Wende, T von Woedtke, KD Weltmann… - Biological …, 2019 - degruyter.com
Reactive oxygen and nitrogen species deposited by cold physical plasma are proposed as
predominant effectors in the interaction between discharge and biomedical application. Most …

Characterization of a melanocyte progenitor population in human interfollicular epidermis

K Michalak-Mićka, VL Büchler, N Zapiórkowska-Blumer… - Cell reports, 2022 - cell.com
It is still unknown whether the human interfollicular epidermis harbors a reservoir of
melanocyte precursor cells. Here, we clearly distinguish between three distinct types of …

Flavone-based hydrazones as new tyrosinase inhibitors: Synthetic imines with emerging biological potential, SAR, molecular docking and drug-likeness studies

RI Alsantali, EU Mughal, N Naeem, MA Alsharif… - Journal of Molecular …, 2022 - Elsevier
Targeting tyrosinase (TYR), a key enzyme responsible for melanogenesis disorders, is a
well-known approach utilized for the development of melanogenesis inhibitor. A variety of …

Cold plasma for microbial safety: Principle, mechanism, and factors responsible

S Punia Bangar, S Suri, P Nayi… - Journal of Food …, 2022 - Wiley Online Library
Elimination of microbiological contamination of food products is predominant for consumer
food safety. Cold plasma (CP) technology has evolved as a unique, cost‐effective, and …

Design, synthesis, and structural characterization of thioflavones and thioflavonols as potential tyrosinase inhibitors: In vitro and in silico studies

EU Mughal, J Ashraf, EM Hussein, Y Nazir… - ACS …, 2022 - ACS Publications
To find new potential tyrosinase inhibitors, a diverse range of 2-arylchromone-4-thione
derivatives (2a–2p) were designed and synthesized by employing a multistep strategy, and …

Synthesis, Anti-Tyrosinase Activity, and Spectroscopic Inhibition Mechanism of Cinnamic Acid–Eugenol Esters

J Li, X Min, X Zheng, S Wang, X Xu, J Peng - Molecules, 2023 - mdpi.com
Tyrosinase plays crucial roles in mediating the production of melanin pigment; thus, its
inhibitors could be useful in preventing melanin-related diseases. To find potential …