Glioblastoma is an aggressive and inevitably recurrent primary intra-axial brain tumor with a
dismal prognosis. The current mainstay of treatment involves maximally safe surgical …

Abstract The Epstein-Barr virus (EBV) is the first oncogenic virus described in human. EBV
infects more than 90% of the human population worldwide, but most EBV infections are …

Molecular heterogeneity is a key feature of glioblastoma that impedes patient stratification
and leads to large discrepancies in mean patient survival. Here, we analyze a cohort of 96 …

RNA sequencing has emerged as a promising approach in cancer prognosis as sequencing
data becomes more easily and affordably accessible. However, it remains challenging to …

Diabetes mellitus is a major debilitating disease whose global incidence is progressively
increasing with currently over 463 million adult sufferers and this figure will likely reach over …

Abstract The oncogenic Epstein-Barr virus (EBV) evades the immune system but has an
Achilles heel: its genome maintenance protein EBNA1. Indeed, EBNA1 is essential for viral …

Epstein-Barr virus (EBV) is a well-characterized oncovirus, associated with several
malignancies. The complex and heterogeneous nature of colorectal cancer (CRC) has led to …

Glioblastoma multiforme (GBM) is an aggressive adult brain tumour with poor prognosis.
Roles for peptidylarginine deiminases (PADs) in GBM have recently been highlighted. Here …

Glioblastoma (GBM) is an aggressive and devastating primary brain cancer which responds
very poorly to treatment. The average survival time of patients is only 14–15 months from …

Background Lifetime exposure to the varicella-zoster virus (VZV) has been consistently
inversely associated with glioma risk, however, the relationship of VZV with survival in adults …