Inflammation and neuropeptides: the connection in diabetic wound healing

L Pradhan, C Nabzdyk, ND Andersen… - Expert reviews in …, 2009 - cambridge.org
Abnormal wound healing is a major complication of both type 1 and type 2 diabetes, with
nonhealing foot ulcerations leading in the worst cases to lower-limb amputation. Wound …

The role of neuromediators and innervation in cutaneous wound healing.

M Ashrafi, M Baguneid, A Bayat - Acta dermato …, 2016 - search.ebscohost.com
The skin is densely innervated with an intricate network of cutaneous nerves,
neuromediators and specific receptors which influence a variety of physiological and …

Nitrite increases glucose-stimulated insulin secretion and islet insulin content in obese type 2 diabetic male rats

S Gheibi, F Bakhtiarzadeh, S Jeddi, K Farrokhfall… - Nitric Oxide, 2017 - Elsevier
Purpose Reduced bioavailability of nitric oxide (NO) is associated with pathogenesis of type
2 diabetes. Nitrite can act as a substrate for generation of systemic NO. The aim of this study …

Autonomic nerve dysfunction and impaired diabetic wound healing: The role of neuropeptides

G Theocharidis, A Veves - Autonomic Neuroscience, 2020 - Elsevier
Lower extremity ulcerations represent a major complication in diabetes mellitus and involve
multiple physiological factors that lead to impairment of wound healing. Neuropeptides are …

Inflammatory and angiogenic abnormalities in diabetic wound healing: role of neuropeptides and therapeutic perspectives

A Tellechea, E Leal, A Veves… - The Open Circulation & …, 2010 - benthamopen.com
Diabetic foot ulceration (DFU) is one of the most costly and debilitating complications of
diabetes and is the leading cause of non-traumatic amputations, affecting 15% of the …

Role of neuropeptides in skin inflammation and its involvement in diabetic wound healing

L da Silva, E Carvalho, MT Cruz - Expert opinion on biological …, 2010 - Taylor & Francis
Importance of the field: In 2010, the world prevalence of diabetes is 6.4%, affecting 285
million adults. Diabetic patients are at risk of developing neuropathy and delayed wound …

Diabetic peripheral neuropathy: role of reactive oxygen and nitrogen species

LS Premkumar, RM Pabbidi - Cell Biochemistry and Biophysics, 2013 - Springer
The prevalence of diabetes has reached epidemic proportions. There are two forms of
diabetes: type 1 diabetes mellitus is due to auto-immune-mediated destruction of pancreatic …

Effects of diabetes on neurotransmission in rat vaginal smooth muscle

A Giraldi, K Persson, V Werkström, P Alm… - International journal of …, 2001 - nature.com
The aim of this work was to characterize the effect of experimental diabetes on
neurotransmission in rat vagina. Female Sprague–Dawley rats were divided into two …

Sensory Nerve Innervation of Epineurial Arterioles of the Sciatic Nerve Containing Calcitonin Gene–Related Peptide: Effect of Streptozotocin‐Induced Diabetes

MA Yorek, LJ Coppey, JS Gellett… - Journal of Diabetes …, 2004 - Wiley Online Library
The authors have determined that epineurial arterioles of the sciatic nerve are innervated by
nonadrenergic, noncholinergic nerves that contribute to the regulation of vasodilation. Using …

DMHF (2,5‐dimethyl‐4‐hydroxy‐3(2H)‐furanone), a volatile food component generated by the Maillard reaction, promotes appetite and changes gene expression in …

I Yokoyama, Y Nakai, Y Suzuki, M Ohata… - Journal of food …, 2020 - Wiley Online Library
Inhalation of odors can affect physiological parameter and change gene expression‐related
specific function. 2, 5‐Dimethyl‐4‐hydroxy‐3 (2H)‐furanone (DMHF) is one of the major …