The extended granin family: structure, function, and biomedical implications
A Bartolomucci, R Possenti, SK Mahata… - Endocrine …, 2011 - academic.oup.com
The chromogranins (chromogranin A and chromogranin B), secretogranins (secretogranin II
and secretogranin III), and additional related proteins (7B2, NESP55, proSAAS, and VGF) …
and secretogranin III), and additional related proteins (7B2, NESP55, proSAAS, and VGF) …
Chromogranin A: from laboratory to clinical aspects of patients with neuroendocrine tumors
P Di Giacinto, F Rota, L Rizza… - International Journal …, 2018 - Wiley Online Library
Background. Neuroendocrine tumors (NETs) are characterized by having behavior and
prognosis that depend upon tumor histology, primary site, staging, and proliferative index …
prognosis that depend upon tumor histology, primary site, staging, and proliferative index …
GC content shapes mRNA storage and decay in human cells
mRNA translation and decay appear often intimately linked although the rules of this
interplay are poorly understood. In this study, we combined our recent P-body transcriptome …
interplay are poorly understood. In this study, we combined our recent P-body transcriptome …
Chromogranins A and B and secretogranin II: evolutionary and functional aspects
M Montero‐Hadjadje, S Vaingankar, S Elias… - Acta …, 2008 - Wiley Online Library
Chromogranins/secretogranins or granins are a class of acidic, secretory proteins that occur
in endocrine, neuroendocrine, and neuronal cells. Granins are the precursors of several …
in endocrine, neuroendocrine, and neuronal cells. Granins are the precursors of several …
The crucial role of chromogranins in storage and exocytosis revealed using chromaffin cells from chromogranin A null mouse
Chromogranins (Cgs) are the major soluble proteins of dense-core secretory vesicles.
Chromaffin cells from Chga null mice [chromogranin A knock-out (CgA-KO)] exhibited∼ …
Chromaffin cells from Chga null mice [chromogranin A knock-out (CgA-KO)] exhibited∼ …
Chromogranin A in the laboratory diagnosis of pheochromocytoma and paraganglioma
R Bílek, P Vlček, L Šafařík, D Michalský, K Novák… - Cancers, 2019 - mdpi.com
This work discusses the clinical performance of chromogranin A (CGA), a commonly
measured marker in neuroendocrine neoplasms, for the diagnosis of pheochromocytoma …
measured marker in neuroendocrine neoplasms, for the diagnosis of pheochromocytoma …
The chromaffin vesicle: advances in understanding the composition of a versatile, multifunctional secretory organelle
Chromaffin vesicles (CV) are highly sophisticated secretory organelles synthesized in
adrenal medullary chromaffin cells. They contain a complex mixture of structural proteins …
adrenal medullary chromaffin cells. They contain a complex mixture of structural proteins …
Cathepsin L colocalizes with chromogranin a in chromaffin vesicles to generate active peptides
N Biswas, JL Rodriguez-Flores, M Courel… - …, 2009 - academic.oup.com
Chromogranin A (CgA), the major soluble protein in chromaffin granules, is proteolytically
processed to generate biologically active peptides including the catecholamine release …
processed to generate biologically active peptides including the catecholamine release …
Secretogranin III directs secretory vesicle biogenesis in mast cells in a manner dependent upon interaction with chromogranin A
P Prasad, AA Yanagihara… - The Journal of …, 2008 - journals.aai.org
Mast cells are granular immunocytes that reside in the body's barrier tissues. These cells
orchestrate inflammatory responses. Proinflammatory mediators are stored in granular …
orchestrate inflammatory responses. Proinflammatory mediators are stored in granular …
Chromogranin A promotes peptide hormone sorting to mobile granules in constitutively and regulated secreting cells: role of conserved N-and C-terminal peptides
M Montero-Hadjadje, S Elias, L Chevalier… - Journal of Biological …, 2009 - ASBMB
Chromogranin A (CgA) has been proposed to play a major role in the formation of dense-
core secretory granules (DCGs) in neuroendocrine cells. Here, we took advantage of unique …
core secretory granules (DCGs) in neuroendocrine cells. Here, we took advantage of unique …