The bacterial cell wall: from lipid II flipping to polymerization

S Kumar, A Mollo, D Kahne, N Ruiz - Chemical reviews, 2022 - ACS Publications
The peptidoglycan (PG) cell wall is an extra-cytoplasmic glycopeptide polymeric structure
that protects bacteria from osmotic lysis and determines cellular shape. Since the cell wall …

Assembly and maintenance of lipids at the bacterial outer membrane

E Lundstedt, D Kahne, N Ruiz - Chemical reviews, 2020 - ACS Publications
The outer membrane of Gram-negative bacteria is essential for their survival in harsh
environments and provides intrinsic resistance to many antibiotics. This membrane is …

Lipopolysaccharide O-antigens—bacterial glycans made to measure

C Whitfield, DM Williams, SD Kelly - Journal of Biological Chemistry, 2020 - ASBMB
Lipopolysaccharides are critical components of bacterial outer membranes. The more
conserved lipid A part of the lipopolysaccharide molecule is a major element in the …

Growth rate is modulated by monitoring cell wall precursors in Bacillus subtilis

Y Sun, S Hürlimann, E Garner - Nature Microbiology, 2023 - nature.com
How bacteria link their growth rate to external nutrient conditions is unknown. To investigate
how Bacillus subtilis cells alter the rate at which they expand their cell walls as they grow …

Inhibition of peptidoglycan synthesis is sufficient for total arrest of staphylococcal cell division

JS Puls, D Brajtenbach, T Schneider, U Kubitscheck… - Science …, 2023 - science.org
Bacterial cell wall biosynthesis is the target of many important antibiotics. Its spatiotemporal
organization is closely coordinated with cell division. However, the role of peptidoglycan …

Photoaffinity labeling chemistries used to map biomolecular interactions

AV West, CM Woo - Israel Journal of Chemistry, 2023 - Wiley Online Library
Photoaffinity labeling (PAL) is one of the few biochemical techniques that can give direct
evidence of biomolecular interactions in cells. Several photoactivatable functional groups …

Structure and mechanism of the lipid flippase MurJ

ACY Kuk, A Hao, SY Lee - Annual review of biochemistry, 2022 - annualreviews.org
Biosynthesis of many important polysaccharides (including peptidoglycan,
lipopolysaccharide, and N-linked glycans) necessitates the transport of lipid-linked …

Lipid transport across bacterial membranes

SI Giacometti, MR MacRae… - Annual Review of …, 2022 - annualreviews.org
The movement of lipids within and between membranes in bacteria is essential for building
and maintaining the bacterial cell envelope. Moving lipids to their final destination is often …

Robust Chiral Metal–Organic Framework Coatings for Self‐Activating and Sustainable Biofouling Mitigation

Z Yu, X Li, Z Wang, Y Fan, W Zhao, D Li… - Advanced …, 2024 - Wiley Online Library
Surface coatings are designed to mitigate pervasive biofouling herald, a new era of surface
protection in complex biological environments. However, existing strategies are plagued by …

In vitro studies of the protein-interaction network of cell-wall lytic transglycosylase RlpA of Pseudomonas aeruginosa

LF Avila-Cobian, S De Benedetti, C Kim… - Communications …, 2022 - nature.com
The protein networks of cell-wall-biosynthesis assemblies are largely unknown. A key class
of enzymes in these assemblies is the lytic transglycosylases (LTs), of which eleven exist in …