Fast food fever: reviewing the impacts of the Western diet on immunity
IA Myles - Nutrition journal, 2014 - Springer
While numerous changes in human lifestyle constitute modern life, our diet has been
gaining attention as a potential contributor to the increase in immune-mediated diseases …
gaining attention as a potential contributor to the increase in immune-mediated diseases …
Immunologic and non-immunologic mechanisms leading to airway remodeling in asthma
L Fang, Q Sun, M Roth - International journal of molecular sciences, 2020 - mdpi.com
Asthma increases worldwide without any definite reason and patient numbers double every
10 years. Drugs used for asthma therapy relax the muscles and reduce inflammation, but …
10 years. Drugs used for asthma therapy relax the muscles and reduce inflammation, but …
Asthma genetics and personalised medicine
DA Meyers, ER Bleecker, JW Holloway… - The lancet Respiratory …, 2014 - thelancet.com
Unbiased genetic approaches, especially genome-wide association studies, have identified
novel genetic targets in the pathogenesis of asthma, but so far these targets account for only …
novel genetic targets in the pathogenesis of asthma, but so far these targets account for only …
T cells in asthma: influences of genetics, environment, and T-cell plasticity
Asthma is classically considered the archetypal TH2 disease, with increased circulating IgE
levels and eosinophilic inflammation being caused by increased levels of TH2-type …
levels and eosinophilic inflammation being caused by increased levels of TH2-type …
Risk of childhood asthma is associated with CpG-site polymorphisms, regional DNA methylation and mRNA levels at the GSDMB/ORMDL3 locus
Single-nucleotide polymorphisms (SNPs) in GSDMB (Gasdermin B) and ORMDL3 (ORMDL
sphingolipid biosynthesis regulator 3) are strongly associated with childhood asthma, but …
sphingolipid biosynthesis regulator 3) are strongly associated with childhood asthma, but …
Association of season of birth with DNA methylation and allergic disease
Background Season of birth influences allergy risk; however, the biological mechanisms
underlying this observation are unclear. The environment affects DNA methylation, with …
underlying this observation are unclear. The environment affects DNA methylation, with …
Epigenetics in immune-mediated pulmonary diseases
Y Liu, H Li, T Xiao, Q Lu - Clinical reviews in allergy & immunology, 2013 - Springer
Immune-mediated pulmonary diseases are a group of diseases that resulted from immune
imbalance initiated by allergens or of unknown causes. Inflammatory responses without …
imbalance initiated by allergens or of unknown causes. Inflammatory responses without …
Sex-and age-dependent DNA methylation at the 17q12-q21 locus associated with childhood asthma
Abstract Chromosomal region 17q12-q21 is one of the best-replicated genome-wide
association study (GWAS) hits and associated with childhood-onset asthma. However, the …
association study (GWAS) hits and associated with childhood-onset asthma. However, the …
Asthma, allergy, and responses to methyl donor supplements and nutrients
S Sharma, A Litonjua - Journal of allergy and clinical immunology, 2014 - Elsevier
After a brief period of stabilization, recent data have shown that the prevalence of asthma
and allergic diseases continues to increase. Atopic diseases are major public health …
and allergic diseases continues to increase. Atopic diseases are major public health …
LINE-1 methylation is associated with an increased risk of ischemic stroke in men
RT Lin, E Hsi, HF Lin, YC Liao… - Current …, 2014 - benthamdirect.com
The level of global DNA methylation may be related to the cerebrovascular disease. The
methylation level of Long Interspersed Nucleotide Element 1 (LINE-1) can represent the …
methylation level of Long Interspersed Nucleotide Element 1 (LINE-1) can represent the …