Obesity-related asthma in children and adolescents

J Reyes-Angel, P Kaviany, D Rastogi… - The Lancet Child & …, 2022 - thelancet.com
There is substantial epidemiological and experimental evidence of an obesity-related
asthma phenotype. Compared to children of healthy weight, children with obesity are at …

Mechanisms and therapeutic strategies for non‐T2 asthma

E Sze, A Bhalla, P Nair - Allergy, 2020 - Wiley Online Library
Non‐T2 asthma is traditionally defined as asthma without features of T2 asthma. The
definition is arbitrary and is generally based on the presence of neutrophils in sputum, or the …

American Association of Clinical Endocrinologists and American College of Endocrinology comprehensive clinical practice guidelines for medical care of patients with …

WT Garvey, JI Mechanick, EM Brett, AJ Garber… - Endocrine Practice, 2016 - Elsevier
Objective Development of these guidelines is mandated by the American Association of
Clinical Endocrinologists (AACE) Board of Directors and the American College of …

[HTML][HTML] Asthma and obesity: two diseases on the rise and bridged by inflammation

M Bantulà, J Roca-Ferrer, E Arismendi… - Journal of clinical …, 2021 - mdpi.com
Asthma and obesity are two epidemics affecting the developed world. The relationship
between obesity and both asthma and severe asthma appears to be weight-dependent …

Toward clinically applicable biomarkers for asthma: an EAACI position paper

Z Diamant, S Vijverberg, K Alving, A Bakirtas… - Allergy, 2019 - Wiley Online Library
Inflammation, structural, and functional abnormalities within the airways are key features of
asthma. Although these processes are well documented, their expression varies across the …

The impact of diet on asthma and allergic diseases

V Julia, L Macia, D Dombrowicz - Nature Reviews Immunology, 2015 - nature.com
The incidence of allergic diseases is increasing, both in developed and developing
countries, concomitantly with the rise in living standards and the adoption of a'western …

Role of IL-17 in asthma pathogenesis and its implications for the clinic

RK Ramakrishnan, S Al Heialy… - Expert review of …, 2019 - Taylor & Francis
Introduction: Asthma is a respiratory disorder typically characterized by T-helper type 2 (Th2)
inflammation that is mediated by cytokines, including IL-4, IL-5, and IL-13 …

Maternal obesity in pregnancy, gestational weight gain, and risk of childhood asthma

E Forno, OM Young, R Kumar, H Simhan… - Pediatrics, 2014 - publications.aap.org
BACKGROUND AND OBJECTIVE: Environmental or lifestyle exposures in utero may
influence the development of childhood asthma. In this meta-analysis, we aimed to assess …

Dietary restriction and exercise improve airway inflammation and clinical outcomes in overweight and obese asthma: a randomized trial

HA Scott, PG Gibson, ML Garg, JJ Pretto… - Clinical & …, 2013 - Wiley Online Library
Background Obesity and asthma are associated conditions; however, the mechanisms
linking the two remain unclear. Few studies have examined the effects of weight loss on …

TH17 cells and corticosteroid insensitivity in severe asthma

Y Xie, PW Abel, TB Casale, Y Tu - Journal of Allergy and Clinical …, 2022 - Elsevier
Asthma is classically described as having either a type 2 (T2) eosinophilic phenotype or a
non-T2 neutrophilic phenotype. T2 asthma usually responds to classical bronchodilation …