JNK is named after c-Jun N-terminal kinase, as it is responsible for phosphorylating c-Jun.
As a member of the mitogen-activated protein kinase (MAPK) family, JNK is also known as …

This review extensively reports data from the literature concerning the complex relationships
between the stress-induced c-Jun N-terminal kinases (JNKs) and the four main cytoskeleton …

Hereditary sensory and autonomic neuropathy 9 (HSAN9) is a rare fatal neurological
disease caused by mis-and nonsense mutations in the gene encoding for Tectonin β …

Abstract C-Jun-N-terminal-kinases (JNKs), members of the mitogen-activated-protein-kinase
family, are significantly linked with neurological and neurodegenerative pathologies and …

Brain size abnormality is correlated with an increased frequency of autism spectrum disorder
(ASD) in offspring. Genetic analysis indicates that heterozygous mutations of the WD repeat …

The WD40 repeat (WDR) domain is present in a wide range of proteins, providing sites for
protein‒protein interactions. Recent studies have shown that WDR proteins play …

Background Autosomal recessive primary microcephaly (MCPH) is a rare
neurodevelopmental disorder characterized primarily by congenital microcephaly and …

Background: Intellectual disability (ID) is a genetically heterogeneous condition, and so far,
1679 human genes have been identified for this phenotype. Countries with a high rate of …

19q13 microdeletion syndrome is a very rare genetic disease characterized by pre-and
postnatal growth retardation, intellectual disability, expressive language impairment …

Background: Brain size abnormality is correlated with increased frequency of autism
spectrum disorder (ASD) in offspring. Genetic analysis indicates that many heterozygous …