A review of effects of atorvastatin in cancer therapy

Z Shaghaghi, M Alvandi, S Farzipour, MR Dehbanpour… - Medical oncology, 2022 - Springer
Cancer is one of the most challenging diseases to manage. A sizeable number of
researches are done each year to find better diagnostic and therapeutic strategies. At the …

[Retracted] Progress of Statin Therapy in the Treatment of Idiopathic Pulmonary Fibrosis

L Kou, P Kou, G Luo, S Wei - Oxidative Medicine and Cellular …, 2022 - Wiley Online Library
Idiopathic pulmonary fibrosis (IPF) is a type of interstitial lung disease (ILD) characterized by
the proliferation of fibroblasts and aberrant accumulation of extracellular matrix. These …

Immediate and late systemic and lung effects of inhaled paraquat in rats

F Amin, A Roohbakhsh, A Memarzia… - Journal of Hazardous …, 2021 - Elsevier
The immediate and the late effects of inhaled Paraquat (PQ) on systemic and lung
inflammation and oxidative stress were investigated. Rats were exposed to saline (control …

Atorvastatin attenuates pulmonary fibrosis in mice and human lung fibroblasts, by the regulation of myofibroblast differentiation and apoptosis

M Yildirim, O Kayalar, E Atahan… - Journal of biochemical …, 2022 - Wiley Online Library
Statins have anti‐inflammatory and antifibrotic effects in addition to cholesterol‐lowering
effect. We aimed to investigate the effect of atorvastatin (ATR) in fibrotic mouse lung and …

Where ferroptosis inhibitors and paraquat detoxification mechanisms intersect, exploring possible treatment strategies

N Rashidipour, S Karami-Mohajeri, A Mandegary… - Toxicology, 2020 - Elsevier
Paraquat (PQ) is a fast-acting and effective herbicide that is used throughout the world to
eliminate weeds. Over the past years, PQ was considered one of the most popular poisoning …

Protective effect of Berberis vulgaris fruit extract against Paraquat-induced pulmonary fibrosis in rats

SA Javad-Mousavi, AA Hemmati, S Mehrzadi… - Biomedicine & …, 2016 - Elsevier
Background Pulmonary fibrosis induced by paraquat (PQ) has caused a large number of
human fatalities all over the world, especially in Asian region. The main potential …

Chlorogenic acid protective effects on paraquat‐induced pulmonary oxidative damage and fibrosis in rats

A Larki‐Harchegani, F Fayazbakhsh… - … of Biochemical and …, 2023 - Wiley Online Library
Paraquat (PQ) is a widely used herbicide that can cause severe oxidative and fibrotic
injuries in lung tissue. Due to the antioxidant and anti‐inflammatory properties of …

Zataria multiflora and Pioglitazone Affect Systemic Inflammation and Oxidative Stress Induced by Inhaled Paraquat in Rats

F Amin, A Memarzia, A Roohbakhsh… - Mediators of …, 2021 - Wiley Online Library
The effects of Zataria multiflora (Z. multiflora) and pioglitazone (a PPAR‐γ agonist) alone
and in combination, on systemic inflammation and oxidative stress induced by inhaled …

Silymarin attenuates paraquat‐induced lung injury via Nrf2‐mediated pathway in vivo and in vitro

F Zhao, D Shi, T Li, L Li, M Zhao - Clinical and Experimental …, 2015 - Wiley Online Library
The present study aims to investigate the impacts and mechanisms of silymarin on paraquat
(PQ)‐induced lung injury in vivo and in vitro. In in vivo experiments, a total of 32 male …

[HTML][HTML] Hydrogen peroxide preconditioning promotes protective effects of umbilical cord vein mesenchymal stem cells in experimental pulmonary fibrosis

T Mahmoudi, K Abdolmohammadi… - Advanced …, 2020 - ncbi.nlm.nih.gov
Purpose: Idiopathic pulmonary fibrosis (IPF) is a progressive lung disorder with few
available treatments. Mesenchymal stem cell therapy (MSCT), an innovative approach, has …