Cellular and Molecular Determinants of Biologic Drugs Resistance and Therapeutic Failure in Inflammatory Bowel Disease
P Puca, I Capobianco, G Coppola… - International Journal of …, 2024 - mdpi.com
The advent of biologic drugs has revolutionized the treatment of Inflammatory Bowel
Disease, increasing rates of response and mucosal healing in comparison to conventional …
Disease, increasing rates of response and mucosal healing in comparison to conventional …
Stress triggers gut dysbiosis via CRH-CRHR1-mitochondria pathway
Y Zhang, X Li, S Lu, H Guo, Z Zhang, H Zheng… - npj Biofilms and …, 2024 - nature.com
Stress can lead to gut dysbiosis in brain-gut axis disordered diseases as irritable bowel
syndrome (IBS), yet the mechanisms how stress transfer from the brain to the gut and disrupt …
syndrome (IBS), yet the mechanisms how stress transfer from the brain to the gut and disrupt …
Mitochondrial dysfunction: unraveling the elusive biology behind anti-TNF response during ulcerative colitis
D Kioroglou, A Peña-Cearra, AM Corraliza, I Seoane… - bioRxiv, 2024 - biorxiv.org
Background Recent studies hint at mitochondrial genes influencing UC patient response to
anti-TNF treatment. We evaluated this hypothesis by following a targeted strategy to identify …
anti-TNF treatment. We evaluated this hypothesis by following a targeted strategy to identify …