Flavonoids as Antiviral Agents for Enterovirus A71 (EV-A71)

S Lalani, CL Poh - Viruses, 2020 - mdpi.com
Flavonoids are natural biomolecules that are known to be effective antivirals. These
biomolecules can act at different stages of viral infection, particularly at the molecular level to …

Health Benefits of Silybum marianum: Phytochemistry, Pharmacology, and Applications

X Wang, Z Zhang, SC Wu - Journal of agricultural and food …, 2020 - ACS Publications
Silybum marianum (SM), a well-known plant used as both a medicine and a food, has been
widely used to treat various diseases, especially hepatic diseases. The seeds and fruits of …

Role of silymarin in cancer treatment: facts, hypotheses, and questions

T Koltai, L Fliegel - Journal of Evidence-Based Integrative …, 2022 - journals.sagepub.com
The flavonoid silymarin extracted from the seeds of Sylibum marianum is a mixture of 6
flavolignan isomers. The 3 more important isomers are silybin (or silibinin), silydianin, and …

Mechanistic insights into the pharmacological significance of silymarin

K Wadhwa, R Pahwa, M Kumar, S Kumar, PC Sharma… - Molecules, 2022 - mdpi.com
Medicinal plants are considered the reservoir of diverse therapeutic agents and have been
traditionally employed worldwide to heal various ailments for several decades. Silymarin is a …

Antiviral activities of silymarin and derivatives

CH Liu, A Jassey, HY Hsu, LT Lin - Molecules, 2019 - mdpi.com
Silymarin flavonolignans are well-known agents that typically possess antioxidative, anti-
inflammatory, and hepatoprotective functions. Recent studies have also documented the …

Silymarin: Not just another antioxidant

FC Camini, DC Costa - Journal of basic and clinical physiology and …, 2020 - degruyter.com
Abstract Silymarin (Silybum marianum; SM), popularly known as milk thistle, is an extract
that has been used for many centuries to treat liver diseases. In recent years, several studies …

Review on oxidative stress relation on COVID-19: Biomolecular and bioanalytical approach

M Ebrahimi, P Norouzi, H Aazami… - International journal of …, 2021 - Elsevier
COVID-19 disease has put life of people in stress worldwide from many aspects. Since the
virus has mutated in absolutely short period of time the challenge to find a suitable vaccine …

[HTML][HTML] Hepatoprotective, antioxidant, anti-inflammatory, and antiviral activities of silymarin against mayaro virus infection

AC Ferraz, LT Almeida, CC da Silva Caetano… - Antiviral Research, 2021 - Elsevier
Infection caused by Mayaro virus (MAYV) is responsible for causing acute nonspecific fever,
in which the majority of patients develop incapacitating and persistent arthritis/arthralgia …

Protective role of flavonoids quercetin and silymarin in the viral-associated inflammatory bowel disease: An updated review

E Zarenezhad, HT Abdulabbas, AS Kareem… - Archives of …, 2023 - Springer
Inflammatory bowel disease (IBD) is a chronic recurrent inflammation of the gastrointestinal
tract (GIT). IBD patients are susceptible to various infections such as viral infections due to …

Antioxidant potential of antiviral drug umifenovir

EV Proskurnina, DY Izmailov, MM Sozarukova… - Molecules, 2020 - mdpi.com
Free radical reactions play an important role in biological functions of living systems. The
balance between oxidants and antioxidants is necessary for the normal homeostasis of cells …