[HTML][HTML] Taurine supplementation as a neuroprotective strategy upon brain dysfunction in metabolic syndrome and diabetes

Z Rafiee, AM García-Serrano, JMN Duarte - Nutrients, 2022 - mdpi.com
Obesity, type 2 diabetes, and their associated comorbidities impact brain metabolism and
function and constitute risk factors for cognitive impairment. Alterations to taurine …

Three-dimensional human neural culture on a chip recapitulating neuroinflammation and neurodegeneration

YJ Kang, YN Diep, M Tran, VTA Tran, G Ambrin… - Nature …, 2023 - nature.com
Neuroinflammation has either beneficial or detrimental effects, depending on risk factors and
neuron–glia interactions in neurological disorders. However, studying neuroinflammation …

[HTML][HTML] Energy metabolism disorder mediated ammonia gas-induced autophagy via AMPK/mTOR/ULK1-Beclin1 pathway in chicken livers

Z Li, Z Miao, L Ding, X Teng, J Bao - Ecotoxicology and Environmental …, 2021 - Elsevier
Ammonia gas is a well-known environmental pollution gas, threatening human health.
Ammonia gas is also one of the most harmful gases to livestock and poultry for many years …

[HTML][HTML] Mitochondrial dysfunction and oxidative stress are involved in the mechanism of methotrexate-induced renal injury and electrolytes imbalance

R Heidari, A Ahmadi, H Mohammadi… - Biomedicine & …, 2018 - Elsevier
Methotrexate is a folate analog used against a wide range of diseases including
malignancies and autoimmune disorders. On the other hand, clinical use of the MTX is …

[HTML][HTML] Betaine treatment protects liver through regulating mitochondrial function and counteracting oxidative stress in acute and chronic animal models of hepatic …

R Heidari, H Niknahad, A Sadeghi… - Biomedicine & …, 2018 - Elsevier
Betaine is a derivative of the amino acid glycine widely investigated for its hepatoprotective
properties against alcoholism. The protective properties of betaine in different other …

Ammonia inhalation impaired immune function and mitochondrial integrity in the broilers bursa of fabricius: implication of oxidative stress and apoptosis

SWA Shah, J Chen, Q Han, Y Xu, M Ishfaq… - … and environmental safety, 2020 - Elsevier
Ammonia (NH 3) is considered as environmental pollutant and toxic agent for animals and
humans including poultry. Previous reports demonstrated that NH 3 suppressed broilers …

[HTML][HTML] The nephroprotective properties of taurine in colistin-treated mice is mediated through the regulation of mitochondrial function and mitigation of oxidative …

R Heidari, S Behnamrad, Z Khodami… - Biomedicine & …, 2019 - Elsevier
Colistin (COL) belongs to the polymixin class of antibiotics used as the last line antibiotic
against drug-resistant infections. However, nephrotoxicity is the major deleterious and dose …

Neuroprotective effect of syringic acid by modulation of oxidative stress and mitochondrial mass in diabetic rats

M Rashedinia, M Alimohammadi… - BioMed Research …, 2020 - Wiley Online Library
Diabetes is a metabolic complaint associated with oxidative stress and dysfunction of
mitochondria. One of the most common complications of diabetes mellitus is neuropathy …

N-acetyl cysteine treatment mitigates biomarkers of oxidative stress in different tissues of bile duct ligated rats

MM Ommati, A Amjadinia, K Mousavi, N Azarpira… - Stress, 2021 - Taylor & Francis
Cholestasis is a multifaceted clinical complication. Obstructive jaundice induced by bile duct
ligation (BDL) is known as an animal model to investigate cholestasis and its associated …

The role and study of mitochondrial impairment and oxidative stress in cholestasis

R Heidari, H Niknahad - Experimental cholestasis research, 2019 - Springer
The blockage of bile flow, cholestasis, could lead to serious clinical outcomes, including
severe liver injury. Accumulation of the cytotoxic molecules, such as bile acids, during …