Vascular development

MW Majesky - Arteriosclerosis, thrombosis, and vascular biology, 2018 - Am Heart Assoc
The vascular system forms as a branching network of endothelial cells that acquire identity
as arterial, venous, hemogenic, or lymphatic. Endothelial specification depends on gene …

The glycoprotein CD147 defines miRNA‐enriched extracellular vesicles that derive from cancer cells

SY Ko, WJ Lee, M Weigert, E Jonasch… - Journal of …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) are ideal for liquid biopsy, but distinguishing cancer cell‐derived
EVs and subpopulations of biomarker‐containing EVs in body fluids has been challenging …

FOXC1 regulates endothelial CD98 (LAT1/4F2hc) expression in retinal angiogenesis and blood-retina barrier formation

T Bhakuni, PR Norden, N Ujiie, C Tan, SK Lee… - Nature …, 2024 - nature.com
Angiogenesis, the growth of new blood vessels from pre-existing vasculature, is essential for
the development of new organ systems, but transcriptional control of angiogenesis remains …

The multifunctional solute carrier 3A2 (SLC3A2) confers a poor prognosis in the highly proliferative breast cancer subtypes

R El Ansari, ML Craze, M Diez-Rodriguez… - British journal of …, 2018 - nature.com
Breast cancer (BC) is a heterogeneous disease characterised by variant biology, metabolic
activity and patient outcome. This study aimed to evaluate the biological and prognostic …

Reporting sex and sex differences in preclinical studies

HS Lu, AM Schmidt, RA Hegele… - … , and vascular biology, 2018 - Am Heart Assoc
e172 Arterioscler Thromb Vasc Biol October 2018 and functions, angiogenesis, and
lymphangiogenesis. These articles studied zebrafish at stages during embryonic or larval …

[HTML][HTML] Immunotherapy using IgE or CAR T cells for cancers expressing the tumor antigen SLC3A2

G Pellizzari, O Martinez, S Crescioli… - … for Immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Background Cancer immunotherapy with monoclonal antibodies and chimeric antigen
receptor (CAR) T cell therapies can benefit from selection of new targets with high levels of …

[HTML][HTML] Role of CD98 in liver disease

BSB Canup, H Song, H Laroui - Annals of Hepatology, 2020 - Elsevier
CD98 is a multifunctional glycoprotein that is involved in various biological processes such
as amino acid transport, cell adhesion, diffusion, adhesion, and proliferation. The role of …

Possible Role of Extracellular Vesicles in Hepatotoxicity of Acetaminophen

M Šrajer Gajdošik, A Kovač Peić, M Begić… - International journal of …, 2022 - mdpi.com
We examined proteomic profiles of rat liver extracellular vesicles (EVs) shed following
treatment with a sub-toxic dose (500 mg/kg) of the pain reliever drug, acetaminophen …

[HTML][HTML] Therapeutic ultrasound plus pulsed electromagnetic field improves recovery from peripheral arterial disease in hypertension

ZY Lu, HS Zhou, ZX Su, J Qi, J Zhang… - American Journal of …, 2017 - ncbi.nlm.nih.gov
The objective of this investigation was to evaluate the therapy effect of combined therapeutic
ultrasound (TUS) treatment and pulsed electromagnetic field (PEMF) therapy on …

Imaging melphalan therapy response in preclinical extramedullary multiple myeloma with 18F-FDOPA and 18F-FDG PET

DK Hathi, EN DeLassus, S Achilefu… - Journal of Nuclear …, 2018 - Soc Nuclear Med
Multiple myeloma (MM) is a debilitating neoplasm of terminally differentiated plasma B cells
that resulted in over 13,000 deaths in 2017 alone. Combination therapies involving …