Molecular mechanisms behind the biological effects of hesperidin and hesperetin for the prevention of cancer and cardiovascular diseases
Hesperidin (Hsd) and its aglycone, hesperetin (Hst), are two flavonoids from citrus species
that have various biological properties, particularly those for the prevention of cancer and …
that have various biological properties, particularly those for the prevention of cancer and …
Hesperidin, a bioflavonoid in cancer therapy: a review for a mechanism of action through the modulation of cell signaling pathways
Cancer represents one of the most frequent causes of death in the world. The current
therapeutic options, including radiation therapy and chemotherapy, have various adverse …
therapeutic options, including radiation therapy and chemotherapy, have various adverse …
Acute and sub-chronic oral toxicity studies of hesperidin isolated from orange peel extract in Sprague Dawley rats
Y Li, AD Kandhare, AA Mukherjee… - Regulatory Toxicology …, 2019 - Elsevier
Citrus sinensis contains glycoside hesperetin-7-rhamnoglucoside (hesperidin) which harbor
an array of therapeutic potentials including antioxidant, anticancer, and anti-inflammatory …
an array of therapeutic potentials including antioxidant, anticancer, and anti-inflammatory …
Hesperidin, a flavanoglycone attenuates experimental diabetic neuropathy via modulation of cellular and biochemical marker to improve nerve functions
A Visnagri, AD Kandhare, S Chakravarty… - Pharmaceutical …, 2014 - Taylor & Francis
Aim: Diabetic neuropathy (DN) is one of the most common long-term complications of
diabetes mellitus and clinically can be characterized by an elevated nociceptive response …
diabetes mellitus and clinically can be characterized by an elevated nociceptive response …
Therapeutic potential of hesperidin and its aglycone hesperetin: Cell cycle regulation and apoptosis induction in cancer models
JMPF de Oliveira, C Santos, E Fernandes - Phytomedicine, 2020 - Elsevier
Background The ability of cancer cells to divide without restriction and to escape
programmed cell death is a feature of the proliferative state. Citrus flavanones are flavonoids …
programmed cell death is a feature of the proliferative state. Citrus flavanones are flavonoids …
[HTML][HTML] Hesperidin, a plant flavonoid accelerated the cutaneous wound healing in streptozotocin-induced diabetic rats: Role of TGF-ß/Smads and Ang-1/Tie-2 …
Background: Delayed wound healing is a diverse, multifactorial, complex and inter-related
complication of diabetes resulting in significant clinical morbidity. Hesperidin possesses …
complication of diabetes resulting in significant clinical morbidity. Hesperidin possesses …
Oxidative stress and cancer; the role of hesperidin, a citrus natural bioflavonoid, as a cancer chemoprotective agent
A Ahmadi, A Shadboorestan - Nutrition and cancer, 2016 - Taylor & Francis
Cancer is the third cause of death worldwide, with complex etiology, and is defined as an
uncontrolled growth of cells. A high proportion of cancer incidence and deaths are due to …
uncontrolled growth of cells. A high proportion of cancer incidence and deaths are due to …
Protective effect of mirtazapine and hesperidin on cyclophosphamide-induced oxidative damage and infertility in rat ovaries
NF Khedr - Experimental biology and medicine, 2015 - journals.sagepub.com
Cyclophosphamide (CP) causes infertility due to ovarian toxicity. The toxicity mechanism
suggests oxidative stress. We assessed whether mirtazapine (MTZ) and hesperidin (HSP) …
suggests oxidative stress. We assessed whether mirtazapine (MTZ) and hesperidin (HSP) …
Therapeutic efficacy of Nano-formulation of lactoperoxidase and lactoferrin via promoting immunomodulatory and apoptotic effects
EM El-Fakharany, M Ashry, AEH Abd-Elaleem… - International Journal of …, 2022 - Elsevier
This study identifies promising potential of a novel and safer nanocombination of bovine milk
lactoperoxidase (LPO) and lactoferrin (LF) to target breast cancer in vitro and in adult female …
lactoperoxidase (LPO) and lactoferrin (LF) to target breast cancer in vitro and in adult female …
Comparison Among Garlic, Berberine, Resveratrol, Hibiscus sabdariffa, Genus Zizyphus, Hesperidin, Red Beetroot, Catha edulis, Portulaca oleracea, and Mulberry …
Diabetes mellitus (DM) and hypertension are 2 of the most prevalent diseases with poor
impact on health status worldwide. In most cases, they coexist with other metabolic disorders …
impact on health status worldwide. In most cases, they coexist with other metabolic disorders …