Key aspects of the past 30 years of protein design

GM Meconi, IR Sasselli, V Bianco… - Reports on Progress …, 2022 - iopscience.iop.org
Proteins are the workhorse of life. They are the building infrastructure of living systems; they
are the most efficient molecular machines known, and their enzymatic activity is still …

Perspective: 4D ultrafast electron microscopy—Evolutions and revolutions

D Shorokhov, AH Zewail - The Journal of chemical physics, 2016 - pubs.aip.org
In this Perspective, the evolutionary and revolutionary developments of ultrafast electron
imaging are overviewed with focus on the “single-electron concept” for probing …

Nanosecond photoemission near the potential barrier of a Schottky emitter

JL Reynolds, Y Israel, AJ Bowman, BB Klopfer… - Physical Review …, 2023 - APS
Nanosecond electron pulses are appealing for ultrafast imaging and electron-gating
applications, where tunable currents and narrow energy spreads are desirable. Here, we …

Circular dichroism and electron microscopy studies in vitro of 33‐mer gliadin peptide revealed secondary structure transition and supramolecular organization

MG Herrera, F Zamarreno, M Costabel, H Ritacco… - …, 2014 - Wiley Online Library
Gliadin, a protein present in wheat, rye, and barley, undergoes incomplete enzymatic
degradation during digestion, producing an immunogenic 33‐mer peptide, LQLQPF …

[HTML][HTML] Self-organization and coherency in biology and medicine

AO Goushcha, TO Hushcha, LN Christophorov… - Open Journal of …, 2014 - scirp.org
Self-organization has proven to be a universal functioning property inherent to the open
systems, including biological entities and living organisms. The flux of energy or matter …

Introducing the Levinthal's protein folding paradox and its solution

L Martínez - Journal of Chemical Education, 2014 - ACS Publications
The protein folding (Levinthal's) paradox states that it would not be possible in a physically
meaningful time to a protein to reach the native (functional) conformation by a random …

[图书][B] 4D Visualization of Matter: Recent Collected Works of Ahmed H Zewail, Nobel Laureate

AH Zewail - 2014 - books.google.com
Ever since the beginning of mankind's efforts to pursue scientific inquiry into the laws of
nature, visualization of the very distant and the very small has been paramount. The …

Using magnets and flexible 3D-printed structures to illustrate protein (un) folding

I Popa, F Saitis - Journal of Chemical Education, 2022 - ACS Publications
Proteins are “magical” workers inside our body, as they accomplish most of the cellular
functions. Here we report on a novel approach to teach protein folding and unfolding, using …

A flexible and adaptive grid algorithm for global optimization utilizing basin hopping Monte Carlo

ML Paleico, J Behler - The Journal of Chemical Physics, 2020 - pubs.aip.org
Global optimization is an active area of research in atomistic simulations, and many
algorithms have been proposed to date. A prominent example is basin hopping Monte …

Theoretical aspects of pressure and solute denaturation of proteins: A Kirkwood-buff-theory approach

A Ben-Naim - The Journal of Chemical Physics, 2012 - pubs.aip.org
A new approach to the problem of pressure-denaturation (PD) and solute-denaturation (SD)
of proteins is presented. The problem is formulated in terms of Le Chatelier principle, and a …