B-cell chronic lymphocytic leukemia (B-CLL) is considered an accumulative disease of
antigen-naive CD5+ B lymphocytes that circulate in the resting state. However, to evaluate …

US7960512B2 - Identification and engineering of antibodies with variant Fc regions and
methods of using same - Google Patents US7960512B2 - Identification and engineering of …

Immune complex-mediated inflammatory responses are initiated by FcγR on phagocytes.
We report in this study that an inhibitory receptor, FcγRIIb2, is expressed on circulating …

Summary Human CD32B (FcγRIIB), the low‐affinity inhibitory Fcγ receptor (FcγR), is highly
homologous in its extracellular domain to CD32A (FcγRIIA), an activating FcγR. Available …

Abstract FcγRIIb (CD32B, Online Mendelian Inheritance in Man 604590), an IgG FcR with a
tyrosine-based inhibitory motif, plays a critical role in the balance of tolerance and …

The receptors on human natural killer 9NK cells which can specifically bind the Fc portion of
immunoglobulin molecules (Fc receptors) have been extensively studied. The best known …

First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
31888221&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Human monocytes/macrophages express three classes of receptors for IgG: FcγRI, FcγRII,
and FcγRIII. The expression and function of these receptors has been extensively studied …

C07K16/283—Immunoglobulins [IGs], eg monoclonal or polyclonal antibodies against
material from animals or humans against receptors, cell surface antigens or cell surface …

2012-08-01 Assigned to MACROGENICS, INC. reassignment MACROGENICS, INC.
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …