The Hypoxia Inducible Factor 1 (HIF-1) plays a major role in the cellular response to hypoxia
by regulating the expression of many genes involved in adaptive processes that allow cell …

Filamin A (FLNa) is an actin-binding protein, which participates in the formation of the
cytoskeleton, anchors a variety of proteins in the cytoskeleton and regulates cell adhesion …

Epitranscriptomic events such as adenosine‐to‐inosine (A‐to‐I) RNA editing by ADAR can
recode mRNA s to translate novel proteins. Editing of the mRNA that encodes actin …

Abstract Hypoxia-inducible factor 1 (HIF-1) is the founding member of a family of
transcription factors that function as master regulators of oxygen homeostasis. HIF-1 is …

ABSTRACT Introduction Calpain-1 and calpain-2 are prototypical classical isoforms of the
calpain family of calcium-activated cysteine proteases. Their substrate proteins participate in …

BACKGROUND: Moyamoya disease (MMD) is a rare progressive vascular disease that
leads to intracranial internal carotid artery stenosis and eventual occlusion. However, its …

Filamin A (FLNA) is a large actin-binding cytoskeletal protein that is important for cell motility
by stabilizing actin networks and integrating them with cell membranes. Interestingly, a C …

Abstract Calpain‐1, a calcium‐activated neutral cysteine proteases, has been reported to be
involved in the formation of pulmonary hypertension. HIF‐1α, an oxygen‐sensitive …

Metastatic uveal melanoma remains incurable at present. We previously demonstrated that
loss of BAP1 gene expression in tumour cells triggers molecular mechanisms of …

Myocardin-related transcription factors A and B (MRTFs) are coactivators of Serum
Response Factor (SRF), which controls fundamental biological processes such as cell …