One is not enough: understanding and modeling polysubstance use

EA Crummy, TJ O'Neal, BM Baskin… - Frontiers in …, 2020 - frontiersin.org
Substance use disorder (SUD) is a chronic, relapsing disease with a highly multifaceted
pathology that includes (but is not limited to) sensitivity to drug-associated cues, negative …

Where is dopamine and how do immune cells see it?: dopamine-mediated immune cell function in health and disease

SM Matt, PJ Gaskill - Journal of Neuroimmune Pharmacology, 2020 - Springer
Dopamine is well recognized as a neurotransmitter in the brain, and regulates critical
functions in a variety of peripheral systems. Growing research has also shown that …

Dopamine in drug abuse and addiction: results from imaging studies and treatment implications

ND Volkow, JS Fowler, GJ Wang, JM Swanson - Molecular psychiatry, 2004 - nature.com
The involvement of dopamine in drug reinforcement is well recognized but its role in drug
addiction is much less clear. Imaging studies have shown that the reinforcing effects of drugs …

[图书][B] Learning: Principles and applications

SB Klein - 2018 - books.google.com
Learning: Principles and Applications by Stephen B. Klein provides students a current,
comprehensive, and engaging introduction to the psychology of learning. Praised for its …

The neurobiology of nicotine addiction: bridging the gap from molecules to behaviour

SR Laviolette, D Van Der Kooy - Nature reviews neuroscience, 2004 - nature.com
Nicotine, the primary psychoactive component of tobacco smoke, produces diverse
neurophysiological, motivational and behavioural effects through several brain regions and …

Endogenous opiates and behavior: 2005

RJ Bodnar, GE Klein - Peptides, 2006 - Elsevier
This paper is the 28th consecutive installment of the annual review of research concerning
the endogenous opioid system, now spanning over a quarter-century of research. It …

Cognitive impairment in substance use disorders

T Ramey, PS Regier - CNS spectrums, 2019 - cambridge.org
Cognitive impairments in substance use disorders have been extensively researched,
especially since the advent of cognitive and computational neuroscience and neuroimaging …

Alcohol use disorders and current pharmacological therapies: the role of GABAA receptors

J Liang, RW Olsen - Acta Pharmacologica Sinica, 2014 - nature.com
Alcohol use disorders (AUD) are defined as alcohol abuse and alcohol dependence, which
create large problems both for society and for the drinkers themselves. To date, no …

Allosteric modulation of family C G-protein-coupled receptors: from molecular insights to therapeutic perspectives

S Urwyler - Pharmacological reviews, 2011 - ASPET
Allosteric receptor modulation is an attractive concept in drug targeting because it offers
important potential advantages over conventional orthosteric agonism or antagonism …

Innovative approaches for the development of antidepressant drugs: current and future strategies

LE Schechter, RH Ring, CE Beyer, ZA Hughes… - NeuroRx, 2005 - Elsevier
Depression is a highly debilitating disorder that has been estimated to affect up to 21% of
the world population. Despite the advances in the treatment of depression with selective …