Fluorouracil (5-FU) is the first-line chemotherapy drug for colorectal cancer but most of the
patients get resistant to the drug on a longer course of treatment. After the successful use of …

Over the past decades, adoptive transfer of T cells has revolutionized cancer
immunotherapy. In particular, T-cell receptor (TCR) engineering of T cells has marked …

A common event upon receptor–ligand engagement is the formation of receptor clusters on
the cell surface, in which signaling molecules are specifically recruited or excluded to form …

Chimeric antigen receptor (CAR) T‐cell transfer is a novel paradigm of adoptive T‐cell
immunotherapy. When coming into contact with a target cancer cell, CAR T‐cell forms a …

The T cell membrane is studded with> 104 T cell receptors (TCRs) that are used to scan
target cells to identify short peptide fragments associated with viral infection or cancerous …

Single-cell motility is spatially heterogeneous and driven by metabolic energy. Directly
linking cell motility to cell metabolism is technically challenging but biologically important …

Chimeric antigen receptor-T (CAR-T) cell therapy is a promising frontier of
immunoengineering and cancer immunotherapy. Methods that detect, quantify, track, and …

Chimeric antigen receptor (CAR)‐T cell therapy has emerged as a promising approach for
cancer treatment. CAR is a synthetic immune receptor that recognizes tumor antigen and …

COVID‐19 caused by SARS‐CoV‐2 is pandemic with a severe morbidity and mortality rate
across the world. Despite the race for effective vaccine and drug against further expansion …

Mechanobiology is an emerging field at the interface of biology and mechanics,
investigating the roles of mechanical forces within biomolecules, organelles, cells, and …