Drugs that target the endocannabinoid system are of interest as pharmacological options to
combat cancer and to improve the life quality of cancer patients. From this perspective …

The endocannabinoid system (ECS) is one of the most crucial systems in the human
organism, exhibiting multi-purpose regulatory character. It is engaged in a vast array of …

Cannabinoids are a family of heterogeneous compounds that mostly interact with receptors
eliciting several physiological effects both in the central and peripheral nervous systems and …

Endocannabinoids are endogenous lipid signaling mediators that participate in a variety of
physiological and pathological processes. 2-Arachidonoylglycerol (2-AG) is the most …

Whereas it is appreciated that cancer cells rewire lipid metabolism to survive and propagate,
the roles of lipid metabolism in metastasis remain largely unknown. In this study, using …

Despite numerous prevention methodologies and treatment options, hepatocellular
carcinoma (HCC) still remains as the third leading life-threatening cancer. It is thus pertinent …

A targeted modulation of the endocannabinoid system is currently discussed as a promising
strategy for cancer treatment. An important enzyme for the endocannabinoid metabolism is …

Simple Summary Cannabinoids have been shown to suppress tumour cell proliferation,
tumour invasion, metastasis, angiogenesis, chemoresistance and epithelial-mesenchymal …

Despite the well-described anticarcinogenic effects of endocannabinoids, the influence of
the endocannabinoid system on tumor angiogenesis is still debated. In the present study …

Derivatives of the plant Cannabis sativa have been used for centuries for both medical and
recreational purposes, as well as industrial. The first proof of its medicinal use comes from …