Purpose Although doxorubicin chemotherapy is commonly applied for treating different
malignant tumors, cardiotoxicity induced by this chemotherapeutic agent restricts its clinical …

Immune reactions are involved in both tumour and normal tissue in response to therapy.
Elevated secretion of certain chemokines, exosomes and cytokines triggers inflammation …

The prevalence of cardiovascular disease, oxidative stress-related complications, and
chronic age-related illnesses is gradually increasing worldwide. Several causes include the …

Background Polydatin and resveratrol are extractives of radix or rhizoma of Polygonum
cuspidatum, and as the glycoside forms, it is a natural precursor of resveratrol. Purpose In …

Cardiovascular diseases are the main cause of mortality and morbidity in the world.
Hypertension, ischemia/reperfusion, diabetes and anti-cancer drugs contribute to heart …

Background: Doxorubicin (DOX), a broad-spectrum chemotherapy drug, is clinically
employed to treat cancers especially for breast cancer and lung cancer. But its clinical …

Cardiotoxicity is one of the major side effects encountered during cancer chemotherapy with
doxorubicin (DOX) and other anthracyclines. Previous studies have shown that oxidative …

Purpose. Although doxorubicin chemotherapeutic drug is commonly used to treat various
solid and hematological tumors, its clinical use is restricted because of its adverse effects on …

Injectable hydrogels with pH-sensitive and self-healing properties have great application
potential in the field of anti-cancer drug carriers. In this work, an injectable hydrogel is …

Vitis vinifera (grape) is one of the “most‐produced fruit” in the world. Grape seeds are a
valuable source of phenolic compounds including resveratrol (RSV). Grape and one of its …