Dilated cardiomyopathy: genetic determinants and mechanisms

EM McNally, L Mestroni - Circulation research, 2017 - Am Heart Assoc
Nonischemic dilated cardiomyopathy (DCM) often has a genetic pathogenesis. Because of
the large number of genes and alleles attributed to DCM, comprehensive genetic testing …

2015 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: The Task Force for the Management of …

Authors/Task Force Members, SG Priori… - Ep …, 2015 - academic.oup.com
The present document has been conceived as the European update to the American
College of Cardiology (ACC)/American Heart Association (AHA)/ESC 2006 Guidelines for …

The clinical use of stress echocardiography in non-ischaemic heart disease: recommendations from the European Association of Cardiovascular Imaging and the …

P Lancellotti, PA Pellikka, W Budts… - European Heart …, 2016 - academic.oup.com
A unique and highly versatile technique, stress echocardiography (SE) is increasingly
recognized for its utility in the evaluation of non-ischaemic heart disease. SE allows for …

2013 ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology Foundation/American Heart Association Task Force on …

CW Yancy, M Jessup, B Bozkurt, J Butler… - Journal of the American …, 2013 - jacc.org
2013 ACCF/AHA Guideline for the Management of Heart Failure: A Report of the American
College of Cardiology Foundation/American Heart Association Task Force on Practice …

Dilated cardiomyopathy and chronic cardiac inflammation: Pathogenesis, diagnosis and therapy

D Harding, MHA Chong, N Lahoti… - Journal of internal …, 2023 - Wiley Online Library
Dilated cardiomyopathy (DCM) is typically defined by left ventricular dilation and systolic
dysfunction in the absence of a clear precipitant. Idiopathic disease is common; up to 50% of …

Genetic mutations and mechanisms in dilated cardiomyopathy

EM McNally, JR Golbus… - The Journal of clinical …, 2013 - Am Soc Clin Investig
Genetic mutations account for a significant percentage of cardiomyopathies, which are a
leading cause of congestive heart failure. In hypertrophic cardiomyopathy (HCM), cardiac …

Genetics of sudden cardiac death

CR Bezzina, N Lahrouchi, SG Priori - Circulation research, 2015 - Am Heart Assoc
Sudden cardiac death occurs in a broad spectrum of cardiac pathologies and is an important
cause of mortality in the general population. Genetic studies conducted during the past 20 …

Genetics and genomics of dilated cardiomyopathy and systolic heart failure

U Tayal, S Prasad, SA Cook - Genome medicine, 2017 - Springer
Heart failure is a major health burden, affecting 40 million people globally. One of the main
causes of systolic heart failure is dilated cardiomyopathy (DCM), the leading global …

Prevalence and cumulative risk of familial idiopathic dilated cardiomyopathy

GS Huggins, DD Kinnamon, GJ Haas, E Jordan… - JAMA, 2022 - jamanetwork.com
Importance Idiopathic dilated cardiomyopathy (DCM) aggregates in families, and early
detection in at-risk family members can provide opportunity to initiate treatment prior to late …

Genetic cardiomyopathies causing heart failure

TJ Cahill, H Ashrafian, H Watkins - Circulation research, 2013 - Am Heart Assoc
Despite the striking advances in medical and surgical therapy, the morbidity, mortality, and
economic burden of heart failure (HF) remain unacceptably high. There is increasing …