Background Sepsis is characterized by a dysregulated immune response and metabolic
alterations, including decreased high-density lipoprotein cholesterol (HDL-C) levels. HDL …

Kidney transplantation is the first-choice treatment for end-stage renal disease (ESRD).
Kidney transplant recipients (KTRs) are at higher risk of experiencing a life-threatening …

In acute kidney injury caused by sepsis (septic AKI), excessive production of inflammatory
mediators is believed to be involved in deterioration of the disease. Renal replacement …

Abdominal adhesion is a frequent clinical issue with a high incidence rate and
consequences following intra-abdominal surgery. Although many anti-adhesion materials …

Several insults can lead to acute kidney injury (AKI) in native kidney and transplant patients,
with diabetes critically contributing as pivotal risk factor. High glucose per se can disrupt …

Acute kidney injury (AKI) is a common consequence of sepsis with a mortality rate of up to
40%. The pathogenesis of septic AKI is complex and involves several mechanisms leading …

By reason of surgical demand, the majority of cardiovascular procedures still depend on the
use of cardiopulmonary bypass (CPB). Due to the nonphysiological state of CPB, it can …

End-stage renal disease (ESRD) is characterized by deep disorders in both innate and
adaptive immune systems that imply unbalance deactivation and immunosuppression. The …

The newly emerged coronavirus (SARS-CoV-2) is virulent, contagious, and has rapidly
gained many mutations, which makes it highly infectious and swiftly transmissible around …

Although experimental models have shown that the innate immune system is a main
contributor to acute kidney injury (AKI), its involvement in human sepsis-associated AKI (SA …