Biological determinants impact the neurovascular toxicity of nicotine and tobacco smoke: A pharmacokinetic and pharmacodynamics perspective
Accumulating evidence suggests that the detrimental effect of nicotine and tobacco smoke
on the central nervous system (CNS) is caused by the neurotoxic role of nicotine on blood …
on the central nervous system (CNS) is caused by the neurotoxic role of nicotine on blood …
Alcohol consumption effect on antiretroviral therapy and HIV-1 pathogenesis: role of cytochrome P450 isozymes
Introduction: Alcohol consumption, which is highly prevalent in HIV-infected individuals,
poses serious concerns in terms of rate of acquisition of HIV-1 infection, HIV-1 replication …
poses serious concerns in terms of rate of acquisition of HIV-1 infection, HIV-1 replication …
Electronic cigarette aerosol induces significantly less cytotoxicity than tobacco smoke
D Azzopardi, K Patel, T Jaunky… - Toxicology …, 2016 - Taylor & Francis
Electronic cigarettes (E-cigarettes) are a potential means of addressing the harm to public
health caused by tobacco smoking by offering smokers a less harmful means of receiving …
health caused by tobacco smoking by offering smokers a less harmful means of receiving …
Effect of benzo (a) pyrene on oxidative stress and inflammatory mediators in astrocytes and HIV-infected macrophages
Background Benzo (a) pyrene (BaP), an important polycyclic aromatic hydrocarbons (PAH)
component of cigarette/tobacco smoking, is known to cause adverse health effects and is …
component of cigarette/tobacco smoking, is known to cause adverse health effects and is …
Nicotine Impairs Macrophage Control of Mycobacterium tuberculosis
X Bai, JA Stitzel, A Bai, CA Zambrano… - American journal of …, 2017 - atsjournals.org
Pure nicotine impairs macrophage killing of Mycobacterium tuberculosis (MTB), but it is not
known whether the nicotine component in cigarette smoke (CS) plays a role. Moreover, the …
known whether the nicotine component in cigarette smoke (CS) plays a role. Moreover, the …
Cytokine profiling of exosomes derived from the plasma of HIV-infected alcohol drinkers and cigarette smokers
Cytokines and chemokines circulate in plasma and may be transferred to distant sites, via
exosomes. HIV infection is associated with dysregulation of cytokines and chemokines …
exosomes. HIV infection is associated with dysregulation of cytokines and chemokines …
Reduced biological effect of e-cigarette aerosol compared to cigarette smoke evaluated in vitro using normalized nicotine dose and RNA-seq-based toxicogenomics
LE Haswell, A Baxter, A Banerjee, I Verrastro… - Scientific Reports, 2017 - nature.com
Electronic cigarettes (e-cigarettes) use has increased globally and could potentially offer a
lower risk alternative to cigarette smoking. Here, we assessed the transcriptional response …
lower risk alternative to cigarette smoking. Here, we assessed the transcriptional response …
Effects of cigarette smoke condensate on oxidative stress, apoptotic cell death, and HIV replication in human monocytic cells
While cigarette smoking is prevalent amongst HIV-infected patients, the effects of cigarette
smoke constituents in cells of myeloid lineage are poorly known. Recently, we have shown …
smoke constituents in cells of myeloid lineage are poorly known. Recently, we have shown …
Luteolin alleviates oxidative stress in chronic obstructive pulmonary disease induced by cigarette smoke via modulation of the TRPV1 and CYP2A13/NRF2 signaling …
L Zhou, T Jian, Y Wan, R Huang, H Fang… - International Journal of …, 2023 - mdpi.com
The current study aims to investigate the therapeutic potential of luteolin (Lut), a naturally
occurring flavonoid found in various medicinal plants, for treating chronic obstructive …
occurring flavonoid found in various medicinal plants, for treating chronic obstructive …
[HTML][HTML] Detection of vascular inflammation and oxidative stress by cotinine in smokers: Measured through interleukin-6 and superoxide dismutase
Purpose Smoking is a significant risk factor in developing cardiovascular disease
pathogenesis through oxidative stress and inflammation mechanisms. This study used …
pathogenesis through oxidative stress and inflammation mechanisms. This study used …