Amino acids in cancer
Abstract Over 90 years ago, Otto Warburg's seminal discovery of aerobic glycolysis
established metabolic reprogramming as one of the first distinguishing characteristics of …
established metabolic reprogramming as one of the first distinguishing characteristics of …
A guide to plasma membrane solute carrier proteins
MD Pizzagalli, A Bensimon… - The FEBS …, 2021 - Wiley Online Library
This review aims to serve as an introduction to the solute carrier proteins (SLC) superfamily
of transporter proteins and their roles in human cells. The SLC superfamily currently …
of transporter proteins and their roles in human cells. The SLC superfamily currently …
Arginine signaling and cancer metabolism
Simple Summary In this review, we describe arginine's role as a signaling metabolite,
epigenetic regulator and mitochondrial modulator in cancer cells, and summarize recent …
epigenetic regulator and mitochondrial modulator in cancer cells, and summarize recent …
Transporter-guided delivery of nanoparticles to improve drug permeation across cellular barriers and drug exposure to selective cell types
Targeted nano-drug delivery systems conjugated with specific ligands to target selective cell-
surface receptors or transporters could enhance the efficacy of drug delivery and therapy …
surface receptors or transporters could enhance the efficacy of drug delivery and therapy …
Advancing cancer treatment by targeting glutamine metabolism—A roadmap
Simple Summary Dysregulated glutamine metabolism is one of the metabolic features
evident in cancer cells when compared to normal cells. Cancer cells utilize glutamine for …
evident in cancer cells when compared to normal cells. Cancer cells utilize glutamine for …
[HTML][HTML] Glutamine transporters in mammalian cells and their functions in physiology and cancer
YD Bhutia, V Ganapathy - Biochimica et Biophysica Acta (BBA)-Molecular …, 2016 - Elsevier
The SLC (solute carrier)-type transporters (~ 400 in number) in mammalian cells consist of
52 distinct gene families, grouped solely based on the amino acid sequence (primary …
52 distinct gene families, grouped solely based on the amino acid sequence (primary …
Nutrient transporters in cancer: relevance to Warburg hypothesis and beyond
Tumor cells have an increased demand for nutrients; this demand is met by increased
availability of nutrients through vasculogenesis and by enhanced cellular entry of nutrients …
availability of nutrients through vasculogenesis and by enhanced cellular entry of nutrients …
Membrane transporters for the special amino acid glutamine: structure/function relationships and relevance to human health
Glutamine together with glucose is essential for body's homeostasis. It is the most abundant
amino acid and is involved in many biosynthetic, regulatory and energy production …
amino acid and is involved in many biosynthetic, regulatory and energy production …
Glutamine transport and mitochondrial metabolism in cancer cell growth
The concept that cancer is a metabolic disease is now well acknowledged: many cancer cell
types rely mostly on glucose and some amino acids, especially glutamine for energy supply …
types rely mostly on glucose and some amino acids, especially glutamine for energy supply …
Nanoengineered sonosensitive platelets for synergistically augmented sonodynamic tumor therapy by glutamine deprivation and cascading thrombosis
Ultrasound (US)-activated sonodynamic therapy (SDT) stands for a distinct antitumor
modality because of its attractive characteristics including intriguing noninvasiveness …
modality because of its attractive characteristics including intriguing noninvasiveness …