Solvatochromic and fluorogenic dyes as environment-sensitive probes: design and biological applications
AS Klymchenko - Accounts of chemical research, 2017 - ACS Publications
Conspectus Fluorescent environment-sensitive probes are specially designed dyes that
change their fluorescence intensity (fluorogenic dyes) or color (eg, solvatochromic dyes) in …
change their fluorescence intensity (fluorogenic dyes) or color (eg, solvatochromic dyes) in …
Design and application of fluorescent probes to detect cellular physical microenvironments
The microenvironment is indispensable for functionality of various biomacromolecules,
subcellular compartments, living cells, and organisms. In particular, physical properties …
subcellular compartments, living cells, and organisms. In particular, physical properties …
[HTML][HTML] Two-photon AIE bio-probe with large Stokes shift for specific imaging of lipid droplets
Lipid droplets are dynamic organelles involved in various physiological processes and their
detection is thus of high importance to biomedical research. Recent reports show that AIE …
detection is thus of high importance to biomedical research. Recent reports show that AIE …
Aggfluor: fluorogenic toolbox enables direct visualization of the multi-step protein aggregation process in live cells
Aberrantly processed or mutant proteins misfold and assemble into a variety of soluble
oligomers and insoluble aggregates, a process that is associated with an increasing number …
oligomers and insoluble aggregates, a process that is associated with an increasing number …
Natural coumarin isomers with dramatically different AIE properties: mechanism and application
Aggregation-induced emission luminogens (AIEgens) are of great importance in
optoelectronics and biomedical fields. However, the popular design philosophy by …
optoelectronics and biomedical fields. However, the popular design philosophy by …
Modulation of fluorescent protein chromophores to detect protein aggregation with turn-on fluorescence
We present a fluorogenic method to visualize misfolding and aggregation of a specific
protein-of-interest in live cells using structurally modulated fluorescent protein …
protein-of-interest in live cells using structurally modulated fluorescent protein …
Development of near-infrared nucleic acid mimics of fluorescent proteins for in vivo imaging of viral RNA with turn-on fluorescence
J Zhang, H Li, B Lin, X Luo, P Yin, T Yi… - Journal of the …, 2021 - ACS Publications
GFP-like fluorescent proteins and their molecular mimics have revolutionized bioimaging
research, but their emissions are largely limited in the visible to far-red region, hampering …
research, but their emissions are largely limited in the visible to far-red region, hampering …
Electrostatic control of photoisomerization pathways in proteins
Adam W. Duster1, Hai Lin2. 1Integrative and Systems Biology, University of Colorado
Denver, Denver, CO, USA, 2Chemistry, University of Colorado Denver, Denver, CO, USA …
Denver, Denver, CO, USA, 2Chemistry, University of Colorado Denver, Denver, CO, USA …
[HTML][HTML] Light-up RNA aptamers and their cognate fluorogens: from their development to their applications
F Bouhedda, A Autour, M Ryckelynck - International journal of molecular …, 2017 - mdpi.com
An RNA-based fluorogenic module consists of a light-up RNA aptamer able to specifically
interact with a fluorogen to form a fluorescent complex. Over the past decade, significant …
interact with a fluorogen to form a fluorescent complex. Over the past decade, significant …
Conical intersection accessibility dictates brightness in red fluorescent proteins
Red fluorescent protein (RFP) variants are highly sought after for in vivo imaging since
longer wavelengths improve depth and contrast in fluorescence imaging. However, the …
longer wavelengths improve depth and contrast in fluorescence imaging. However, the …