[HTML][HTML] Discovery and resupply of pharmacologically active plant-derived natural products: A review

AG Atanasov, B Waltenberger… - Biotechnology …, 2015 - Elsevier
Medicinal plants have historically proven their value as a source of molecules with
therapeutic potential, and nowadays still represent an important pool for the identification of …

Computer-aided drug discovery and development (CADDD): in silico-chemico-biological approach

IM Kapetanovic - Chemico-biological interactions, 2008 - Elsevier
It is generally recognized that drug discovery and development are very time and resources
consuming processes. There is an ever growing effort to apply computational power to the …

The future is written: impact of scripts on the cognition, selection, knowledge and transmission of medicinal plant use and its implications for ethnobotany and …

M Leonti - Journal of Ethnopharmacology, 2011 - Elsevier
AIM OF THE STUDY: Apart from empirically learned medicinal and pharmacological
properties, the selection of medicinal plants is dependent on cognitive features, ecological …

Applications of metabolomics in drug discovery and development

DS Wishart - Drugs in R & D, 2008 - Springer
Metabolomics is a relatively new field of 'omics' technology that is primarily concerned with
the global or system-wide characterization of small molecule metabolites using technologies …

Botanical immunodrugs: scope and opportunities

B Patwardhan, M Gautam - Drug discovery today, 2005 - Elsevier
Modulation of the immune system can be addressed through a variety of specific and non-
specific approaches. Many agents of synthetic and natural origin have stimulatory …

Virtual screening for the discovery of bioactive natural products

JM Rollinger, H Stuppner, T Langer - Natural compounds as drugs …, 2008 - Springer
In this survey the impact of the virtual screening concept is discussed in the field of drug
discovery from nature. Confronted by a steadily increasing number of secondary metabolites …

Acetylcholinesterase inhibitory activity of scopolin and scopoletin discovered by virtual screening of natural products

JM Rollinger, A Hornick, T Langer… - Journal of medicinal …, 2004 - ACS Publications
For the targeting selection of acetylcholinesterase (AChE) inhibitors from natural sources we
generated a structure-based pharmacophore model utilizing an in silico filtering experiment …

The role of pharmacognosy in modern medicine and pharmacy

WP Jones, YW Chin, AD Kinghorn - Current drug targets, 2006 - ingentaconnect.com
This review details the contribution to modern medicine and pharmacy made by natural
products and drugs derived from natural products, with an emphasis on essential medicines …

Anti-neuroinflammatory effect of Sophoraflavanone G from Sophora alopecuroides in LPS-activated BV2 microglia by MAPK, JAK/STAT and Nrf2/HO-1 signaling …

C Guo, L Yang, CX Wan, YZ Xia, C Zhang, MH Chen… - Phytomedicine, 2016 - Elsevier
Background: Neuroinflammation plays a vital role in Alzheimer's disease (AD) and other
neurodegenerative conditions. Sophora alopecuroides is widely used in traditional Uighur's …

Current strategies for drug discovery through natural products

AL Harvey, RL Clark, SP Mackay… - Expert opinion on drug …, 2010 - Taylor & Francis
Importance to the field: Natural products are the most consistently successful source of drug
leads, both historically and currently. Despite this, the use of natural products in industrial …