Potential roles of dental pulp stem cells in neural regeneration and repair

L Luo, Y He, X Wang, B Key, BH Lee… - Stem cells …, 2018 - Wiley Online Library
This review summarizes current advances in dental pulp stem cells (DPSCs) and their
potential applications in the nervous diseases. Injured adult mammalian nervous system has …

Dental stem cells: recent progresses in tissue engineering and regenerative medicine

J Botelho, MA Cavacas, V Machado… - Annals of Medicine, 2017 - Taylor & Francis
Since the disclosure of adult mesenchymal stem cells (MSCs), there have been an intense
investigation on the characteristics of these cells and their potentialities. Dental stem cells …

Advances and perspectives in dental pulp stem cell based neuroregeneration therapies

J Luzuriaga, Y Polo, O Pastor-Alonso… - International journal of …, 2021 - mdpi.com
Human dental pulp stem cells (hDPSCs) are some of the most promising stem cell types for
regenerative therapies given their ability to grow in the absence of serum and their realistic …

Dental pulp stem cells derived from adult human third molar tooth: a brief review

A Al Madhoun, S Sindhu, D Haddad, M Atari… - Frontiers in Cell and …, 2021 - frontiersin.org
The fields of regenerative medicine and stem cell-based tissue engineering have the
potential of treating numerous tissue and organ defects. The use of adult stem cells is of …

Clinical potential of dental pulp stem cells in pulp regeneration: current endodontic progress and future perspectives

KH Kwack, HW Lee - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
Dental caries is a common disease that not only destroys the rigid structure of the teeth but
also causes pulp necrosis in severe cases. Once pulp necrosis has occurred, the most …

The potential therapy with dental tissue-derived mesenchymal stem cells in Parkinson's disease

Z Xiao, T Lei, Y Liu, Y Yang, W Bi, H Du - Stem cell research & therapy, 2021 - Springer
Abstract Parkinson's disease (PD), the second most common neurodegenerative disease
worldwide, is caused by the loss of dopaminergic (DAergic) neurons in the substantia nigra …

Application of dental pulp stem cells for bone and neural tissue regeneration in oral and maxillofacial region

Y Fujii, A Hatori, D Chikazu… - Stem Cells …, 2023 - Wiley Online Library
In the oral and maxillofacial region, the treatment of severe bone defects, caused by
fractures, cancers, congenital abnormalities, etc., remains a great challenge. In addition …

Deciduous DPSCs ameliorate MPTP-mediated neurotoxicity, sensorimotor coordination and olfactory function in parkinsonian mice

C Simon, QF Gan, P Kathivaloo, NA Mohamad… - International Journal of …, 2019 - mdpi.com
Parkinson's disease (PD) is a neurodegenerative disorder defined by progressive
deterioration of dopaminergic neurons in the substantia nigra pars compacta (SNpc). Dental …

Sustainable effects of human dental pulp stem cell transplantation on diabetic polyneuropathy in streptozotocine-induced type 1 diabetes model mice

M Hata, M Omi, Y Kobayashi, N Nakamura, M Miyabe… - Cells, 2021 - mdpi.com
Dental pulp stem cells (DPSCs) are suitable for use in regenerative medicine.
Cryopreserved human DPSCs (hDPSCs) ameliorate diabetic polyneuropathy, and the …

Neuroimmunomodulatory properties of DPSCs in an in vitro model of Parkinson's disease

N Gnanasegaran, V Govindasamy, V Mani… - IUBMB …, 2017 - Wiley Online Library
In neurodegenerative diseases, such as Alzheimer's and Parkinson's, microglial cell
activation is thought to contribute to their degeneration by producing neurotoxic compounds …