Mesenchymal stem cell (MSC) is an intensely studied stem cell type applied for cardiac
repair. For decades, the preclinical researches on animal model and clinical trials have …

The spectrum of ischaemic cardiomyopathy, encompassing acute myocardial infarction to
congestive heart failure is a significant clinical issue in the modern era. This group of …

Background: In addition to scalability, human embryonic stem cells (hESCs) have the unique
advantage of allowing their directed differentiation toward lineage-specific cells. Objectives …

Aims Comparative studies suggest that stem cells committed to a cardiac lineage are more
effective for improving heart function than those featuring an extra-cardiac phenotype. We …

Systemic injection into blood vessels is the most common method of drug administration.
However, targeting drugs to the heart is challenging, owing to its dynamic mechanical …

The goal of cardiac tissue engineering is to restore function to the damaged myocardium
with regenerative constructs. Human embryonic stem cell–derived cardiomyocytes (hESC …

The first review on biomaterials for the treatment of myocardial infarction (MI) was written in
2006. In the last 5 years, the general approaches for biomaterial treatment of MI and …

Worldwide research on electrospinning enabled it as a versatile technique for producing
nanofibers with specified physio-chemical characteristics suitable for diverse biomedical …

Cell delivery to the infarcted heart has emerged as a promising therapy, but is limited by very
low acute retention and engraftment of cells. The objective of this study was to compare a …

Aim There is now compelling evidence that cells committed to a cardiac lineage are most
effective for improving the function of infarcted hearts. This has been confirmed by our pre …