Metal compounds against neglected tropical diseases

YC Ong, S Roy, PC Andrews, G Gasser - Chemical reviews, 2018 - ACS Publications
Many first-line treatments for neglected tropical diseases identified by the World Health
Organization (WHO) are limited by one or more of the following: the development of drug …

The estradiol pharmacophore: ligand structure-estrogen receptor binding affinity relationships and a model for the receptor binding site

GM Anstead, KE Carlson, JA Katzenellenbogen - Steroids, 1997 - Elsevier
The accumulated knowledge on the binding of estradiol (E2) and its analogs and the results
of affinity-labeling studies have been reviewed and are used herein to derive a binding site …

Synthesis, biochemical properties and molecular modelling studies of organometallic specific estrogen receptor modulators (SERMs), the ferrocifens and …

S Top, A Vessières, G Leclercq, J Quivy… - … A European Journal, 2003 - Wiley Online Library
A series of ferrocene derivatives based upon the structure of the antiestrogenic drug
tamoxifen or of its active metabolite hydroxytamoxifen has been prepared and named by …

Luminescent biological probes derived from ruthenium (II) estradiol polypyridine complexes

KKW Lo, TKM Lee, JSY Lau, WL Poon… - Inorganic …, 2008 - ACS Publications
Four luminescent ruthenium (II) polypyridine estradiol complexes [Ru (N∧ N) 2 (bpy-
estradiol)](PF6) 2 (N∧ N= 2, 2 '-bipyridine (bpy), 4, 7-diphenyl-1, 10-phenanthroline (Ph2 …

Studies on organometallic selective estrogen receptor modulators.(SERMs) Dual activity in the hydroxy-ferrocifen series

S Top, A Vessieres, C Cabestaing, I Laios… - Journal of …, 2001 - Elsevier
Synthesis of 7, a ferrocene derivative of the antiestrogenic drug hydroxytamoxifen bearing a
basic chain-O (CH2) nN (CH3) 2 with n= 4 is presented, together with both studies of its …

A transition metal carbonyl probe for use in a highly specific and sensitive SERS-based assay for glucose

KV Kong, Z Lam, WKO Lau, WK Leong… - Journal of the American …, 2013 - ACS Publications
A triosmium carbonyl cluster–boronic acid conjugate is used as a secondary carbohydrate
probe in a SERS-based assay. The assay does not require conjugation of the metal …

Ferrocenyl hydroxytamoxifen: a prototype for a new range of oestradiol receptor site-directed cytotoxics

S Top, J Tang, A Vessières, D Carrez… - Chemical …, 1996 - pubs.rsc.org
Ferrocenyl hydroxytamoxifen: a prototype for a new range of oestradiol receptor site-directed
cytotoxics Page 1 Ferrocenyl hydroxytamoxifen: a prototype for a new range of oestradiol …

Subcellular IR imaging of a metal–carbonyl moiety using photothermally induced resonance

C Policar, JB Waern, MA Plamont… - Angewandte Chemie …, 2011 - Wiley Online Library
The most widely developed techniques for bio-imaging are those based on fluorescence
spectroscopy. However, vibrational spectroscopic techniques, including infrared (IR) …

[PDF][PDF] Metal Carbonyl–Gold Nanoparticle Conjugates for Live‐Cell SERS Imaging

KV Kong, Z Lam, WD Goh, WK Leong… - Angewandte Chemie …, 2012 - academia.edu
The field of bioorganometallic chemistry, the junction of organometallic chemistry and
biology, is coming of age. In particular, applications of metal carbonyl compounds in …

Rhenium Carbonyl Complexes of. beta.-Estradiol Derivatives with High Affinity for the Estradiol Receptor: An Approach to Selective Organometallic …

S Top, H El Hafa, A Vessieres, J Quivy… - Journal of the …, 1995 - ACS Publications
The complexes 17a-[(C= CC5H4) M (CO) 3]-estradiol, M= Re (17) and Mn (18), were
prepared either by reaction of (LiC= CCsH4) M (CO) 3 with estrone or by the Pd-catalyzed …