Psoriasis is a recurring inflammatory skin condition characterized by scaly, red patches on
the skin. It affects approximately 3% of the US population and is associated with histological …

The mammalian family of basic helix-loop-helix-PER-ARNT-SIM (bHLH-PAS) transcription
factors possess the ability to sense and respond to diverse environmental and physiological …

In vitro investigations have revealed that consumption of selenium can considerably
decrease the expression of IFN-g in Th1 cells. A low plasma selenium content has been …

The S100A8/A9 heterocomplex is an abundant damage-associated molecular pattern and
mainly expressed by monocytes, inflammatory activated keratinocytes and neutrophilic …

Apremilast (APM) is a novel drug for the treatment of psoriasis and psoriatic arthritis. APM is
a phosphodiesterase 4 (PDE4) inhibitor, raising intracellular cAMP levels and thereby …

Topical treatment plays a crucial role in psoriasis management, with non-adherence being a
major barrier to treatment success. The fixed-dose combination of calcipotriol (CAL) and …

PAS domains are ubiquitous in biology. They perform critically important roles in sensing
and transducing a wide variety of environmental signals, and through their ability to bind …

The study on psoriasis disease helps improve the condition and treatment options day by
day in dermatology. In the current scenario, research is ongoing to make the best …

While the COVID-19 pandemic also affected the work of regulatory authorities, the US Food
and Drug Administration approved a total of 53 new drugs in 2020, one of the highest …

Psoriasis, a chronic immune-mediated inflammatory skin disease, influences approximately
2–3% of the world's population. At present, the etiology of psoriasis remains unclear and …