Microbial L-asparaginase for application in acrylamide mitigation from food: Current research status and future perspectives
R Jia, X Wan, X Geng, D Xue, Z Xie, C Chen - Microorganisms, 2021 - mdpi.com
L-asparaginase (EC 3.5. 1.1) hydrolyzes L-asparagine to L-aspartic acid and ammonia,
which has been widely applied in the pharmaceutical and food industries. Microbes have …
which has been widely applied in the pharmaceutical and food industries. Microbes have …
Exploring current scenario and developments in the field of microbial L-asparaginase production and applications: A review
PG Patel, HZ Panseriya, AK Vala, BP Dave… - Process …, 2022 - Elsevier
L-asparaginase, an amidohydrolase that catalyses break down of L-asparagine into aspartic
acid and ammonia, is one of the most prominent biopharmaceuticals. L-asparaginase (LA) …
acid and ammonia, is one of the most prominent biopharmaceuticals. L-asparaginase (LA) …
Potential of anti-cancer activity of secondary metabolic products from marine fungi
E Noman, MM Al-Shaibani, MA Bakhrebah… - Journal of Fungi, 2021 - mdpi.com
The promising feature of the fungi from the marine environment as a source for anticancer
agents belongs to the fungal ability to produce several compounds and enzymes which …
agents belongs to the fungal ability to produce several compounds and enzymes which …
Engineering and expression strategies for optimization of L-Asparaginase development and production
AN Shishparenok, YA Gladilina… - International Journal of …, 2023 - mdpi.com
Genetic engineering for heterologous expression has advanced in recent years. Model
systems such as Escherichia coli, Bacillus subtilis and Pichia pastoris are often used as host …
systems such as Escherichia coli, Bacillus subtilis and Pichia pastoris are often used as host …
Anticancer Asparaginases: perspectives in using filamentous Fungi as cell factories
PHD Garcia, TA Costa-Silva, MM Gómez, FJ Contesini… - Catalysts, 2023 - mdpi.com
The enzyme L-asparaginase (L-asparagine amidohydrolase) catalyzes the breakdown of L-
asparagine into aspartate and ammonia, which leads to an anti-neoplastic activity stemming …
asparagine into aspartate and ammonia, which leads to an anti-neoplastic activity stemming …
Production, characterization and techno-economic evaluation of Aspergillus fusant l-asparaginase
Protoplast fusion is one of the most reliable methods of introducing desirable traits into
industrially-promising fungal strains. It harnesses the entire genomic repertoire of fusing …
industrially-promising fungal strains. It harnesses the entire genomic repertoire of fusing …
Interspecific protoplast fusion of atmospheric and room-temperature plasma mutants of Aspergillus generates an L-asparaginase hyper-producing hybrid with techno …
A Asitok, M Ekpenyong, E Akwagiobe… - Preparative …, 2023 - Taylor & Francis
The axenic culture of Aspergillus candidus (Asp-C) produced an anti-leukemic L-
asparaginase while Aspergillus sydowii (Asp-S) produced the acrylamide-reduction type …
asparaginase while Aspergillus sydowii (Asp-S) produced the acrylamide-reduction type …