Cancer is one of the major healthcare challenges across the globe. Several anticancer
drugs are available on the market but they either lack specificity or have poor safety, severe …

Malaria poses a severe public health risk and a significant economic burden in disease-
endemic countries. One of the most severe issues in malaria control is the development of …

Many researchers around the world are working on the development of novel anticancer
drugs with different mechanisms of action. In this case, coumarin is a highly promising …

Coumarin hybrids have been designed and synthesized as an important new strategy in the
field of medicinal chemistry. Coumarin core has been shown to form various compounds to …

Microtubules are cylindrical protein polymers formed from α β-tubulin heterodimers in the
cytoplasm of eukaryotic cells. Microtubule disturbance may cause cell cycle arrest in the …

This review-based study presents the anticancer potential of pyrazole-based copper
complexes, aiming to evaluate their mechanistic action at the molecular level and find …

We have described solvent-free preparation of new pyrano [2, 3-c]-pyrazole-5-carbonitriles
(1-10) from the reaction of 1, 3-diketo ester, aryl hydrazine, aromatic aldehyde, and …

The main objective of this research work is to discover novel and efficient phytochemical
substances from endophytic fungus found in medicinal plants. Curvularia geniculata L.(C …

Coumarin is a versatile scaffold with outstanding biological potential and played a key role
in the field of medicine. The benzopyran-2-one ring bearing heterocycles are known for …

Aim: Human carbonic anhydrase (CA, EC 4.2. 1.1) isoforms IX and XII are validated
antitumor/antimetastatic drug and tumor imaging targets with sulfonamide inhibitors and …