Advanced glycation end-products (AGEs) constitute a non-homogenous, chemically diverse
group of compounds formed either exogeneously or endogeneously on the course of …

Amyloid-β (Aβ) is the predominant pathologic protein in Alzheimer's disease (AD). The
production and deposition of Aβ are important factors affecting AD progression and …

The receptor for advanced glycation end-products (RAGE) is a multiligand pattern
recognition receptor implicated in diverse chronic inflammatory states. RAGE binds and …

Obesity and diabetes are leading causes of cardiovascular morbidity and mortality. Although
extensive strides have been made in the treatments for non-diabetic atherosclerosis and its …

CD146 was originally identified as a melanoma cell adhesion molecule (MCAM) and highly
expressed in many tumors and endothelial cells. However, the evidence that CD146 acts as …

The receptor for advanced glycation endproducts (RAGE) is an ubiquitous, transmembrane,
immunoglobulin-like receptor that exists in multiple isoforms and binds to a diverse range of …

Diabetes induces the onset and progression of renal injury through causing hemodynamic
dysregulation along with abnormal morphological and functional nephron changes. The …

In Alzheimer disease (AD), amyloid β peptide (Aβ) accumulates in plaques in the brain.
Receptor for advanced glycation end products (RAGE) mediates Aβ-induced perturbations …

ABSTRACT RAGE is a key molecule in the onset and sustainment of the inflammatory
response. New studies indicate that RAGE might represent a new link between the innate …

The receptor for advanced glycation endproducts (RAGE) was first described as a signal
transduction receptor for advanced glycation endproducts (AGEs), the products of …