[HTML][HTML] Promoting health and longevity through diet: from model organisms to humans

L Fontana, L Partridge - Cell, 2015 - cell.com
Reduced food intake, avoiding malnutrition, can ameliorate aging and aging-associated
diseases in invertebrate model organisms, rodents, primates, and humans. Recent findings …

The naked truth: a comprehensive clarification and classification of current 'myths' in naked mole‐rat biology

R Buffenstein, V Amoroso, B Andziak… - Biological …, 2022 - Wiley Online Library
The naked mole‐rat (Heterocephalus glaber) has fascinated zoologists for at least half a
century. It has also generated considerable biomedical interest not only because of its …

Naked mole-rat mortality rates defy Gompertzian laws by not increasing with age

JG Ruby, M Smith, R Buffenstein - elife, 2018 - elifesciences.org
The longest-lived rodent, the naked mole-rat (Heterocephalus glaber), has a reported
maximum lifespan of> 30 years and exhibits delayed and/or attenuated age-associated …

The naked mole-rat algorithm

R Salgotra, U Singh - Neural Computing and Applications, 2019 - Springer
This work proposes a new swarm intelligent nature-inspired algorithm called naked mole-rat
(NMR) algorithm. This NMR algorithm mimics the mating patterns of NMRs present in nature …

Animal models of aging research: implications for human aging and age-related diseases

SJ Mitchell, M Scheibye-Knudsen… - Annu. Rev. Anim …, 2015 - annualreviews.org
Aging is characterized by an increasing morbidity and functional decline that eventually
results in the death of an organism. Aging is the largest risk factor for numerous human …

Alternative animal models of aging research

S Holtze, E Gorshkova, S Braude… - Frontiers in Molecular …, 2021 - frontiersin.org
Most research on mechanisms of aging is being conducted in a very limited number of
classical model species, ie, laboratory mouse (Mus musculus), rat (Rattus norvegicus …

Oxidative damage, ageing, and life-history evolution: where now?

C Selman, JD Blount, DH Nussey… - Trends in ecology & …, 2012 - cell.com
The idea that resources are limited and animals can maximise fitness by trading costly
activities off against one another forms the basis of life-history theory. Although investment in …

Epigenetic aging of the demographically non-aging naked mole-rat

C Kerepesi, MV Meer, J Ablaeva, VG Amoroso… - Nature …, 2022 - nature.com
The naked mole-rat (NMR) is an exceptionally long-lived rodent that shows no increase of
mortality with age, defining it as a demographically non-aging mammal. Here, we perform …

Naked mole-rat very-high-molecular-mass hyaluronan exhibits superior cytoprotective properties

M Takasugi, D Firsanov, G Tombline, H Ning… - Nature …, 2020 - nature.com
Abstract Naked mole-rat (NMR), the longest-living rodent, produces very-high-molecular-
mass hyaluronan (vHMM-HA), compared to other mammalian species. However, it is …

Neoteny, prolongation of youth: from naked mole rats to “naked apes”(humans)

VP Skulachev, S Holtze, MY Vyssokikh… - Physiological …, 2017 - journals.physiology.org
It has been suggested that highly social mammals, such as naked mole rats and humans,
are long-lived due to neoteny (the prolongation of youth). In both species, aging cannot …