Although fibrosis is a common pathological feature of most end-stage organ diseases, its
pathogenesis remains unclear. There is growing evidence that mitochondrial dysfunction …

Idiopathic pulmonary fibrosis (IPF) is a devastating lung disease of unknown etiology. It is
characterized by deposition of extracellular matrix proteins, like collagen and fibronectin in …

Vascular dysfunction is a hallmark of chronic diseases in elderly. The contribution of the
vasculature to lung repair and fibrosis is not fully understood. Here, we performed an …

Pulmonary fibrosis is a chronic and fatal lung disease that significantly impacts the aging
population globally. To date, anti-fibrotic, immunosuppressive, and other adjunct therapy …

Mitochondrial biology has seen a surge in popularity in the past 5 years, with the emergence
of numerous new avenues of exciting mitochondria-related research including …

The COVID‐19 pandemic rapidly spread around the world following the first reports in
Wuhan City, China in late 2019. The disease, caused by the novel SARS‐CoV‐2 virus, is …

Aging is an inevitable and complex natural phenomenon due to the increase in age. Cellular
senescence means a non-proliferative but viable cellular physiological state. It is the basis of …

Introduction Idiopathic pulmonary fibrosis (IPF) is a progressive fibrosing interstitial lung
disease of unknown aetiology and cure. Recent studies have reported a dysregulation of …

Mechanisms underlying the pathogenesis of pulmonary fibrosis remain incompletely
understood. Emerging evidence suggests changes in mitochondrial quality control are a …

Myofibroblasts are the major cellular source of collagen, and their accumulation—via
differentiation from fibroblasts and resistance to apoptosis—is a hallmark of tissue fibrosis …