[HTML][HTML] Dysregulated signalling pathways in innate immune cells with cystic fibrosis mutations

S Lara-Reyna, J Holbrook, HH Jarosz-Griffiths… - Cellular and Molecular …, 2020 - Springer
Cystic fibrosis (CF) is one of the most common life-limiting recessive genetic disorders in
Caucasians, caused by mutations in the cystic fibrosis transmembrane conductance …

NETosis− Dr. Jekyll and Mr. Hyde in inflammation

L Lauková, B Konečná - Journal of Applied Biomedicine, 2018 - Elsevier
Neutrophils play an important role as the central mediators of the innate immune defence
response, providing the first line of host protection. It was shown that these cells can trap and …

Calprotectin-mediated zinc chelation inhibits Pseudomonas aeruginosa protease activity in cystic fibrosis sputum

DM Vermilyea, AW Crocker, AH Gifford… - Journal of …, 2021 - Am Soc Microbiol
Pseudomonas aeruginosa induces pathways indicative of low zinc availability in the cystic
fibrosis (CF) lung environment. To learn more about P. aeruginosa zinc access in CF, we …

[HTML][HTML] Bactericidal/permeability-increasing protein instructs dendritic cells to elicit Th22 cell response

S Bülow, KU Ederer, JM Holzinger, L Zeller, M Werner… - Cell Reports, 2024 - cell.com
Neutrophil-derived bactericidal/permeability-increasing protein (BPI) is known for its
bactericidal activity against gram-negative bacteria and neutralization of lipopolysaccharide …

Predicting bacterial infection risk in patients with ANCA-associated vasculitis in southwest China: development of a new nomogram

N Zhang, J Sun, C Ji, X Bao, C Yuan - Clinical Rheumatology, 2022 - Springer
Objectives The aim of this study was to develop and assess a risk nomogram of bacterial
infection in patients with ANCA-associated vasculitis (AAV) in southwest China. Method We …

Low-avidity autoantibodies against bactericidal/permeability-increasing protein occur in gram-negative and gram-positive bacteremia

J Theprungsirikul, JT Thaden, RM Wierzbicki… - Infection and …, 2020 - Am Soc Microbiol
Antibody autoreactivity against bactericidal/permeability-increasing protein (BPI) is strongly
associated with Pseudomonas aeruginosa infection in cystic fibrosis (CF), non-CF …