Phylodynamics requires an interdisciplinary understanding of phylogenetics, epidemiology,
and statistical inference. It has also experienced more intense application than ever before …

Background Tracking recent transmission is a vital part of controlling widespread pathogens
such as Mycobacterium tuberculosis. Multiple methods with specific performance …

When viruses spread, outbreaks can be spawned in previously unaffected regions.
Depending on the time and mode of introduction, each regional outbreak can have its own …

Birth–death stochastic processes are the foundations of many phylogenetic models and are
widely used to make inferences about epidemiological and macroevolutionary dynamics …

Both normal tissue development and cancer growth are driven by a branching process of
cell division and mutation accumulation that leads to intra-tissue genetic heterogeneity …

Avian influenza viruses can cause severe disease in domestic and wild birds and are a
pandemic threat. Phylodynamics is the study of how epidemiological, evolutionary, and …

Drug resistant HIV is a major threat to the long-term efficacy of antiretroviral treatment.
Around 10% of ART-naïve patients in Europe are infected with drug-resistant HIV type 1 …

Survivorship biases can generate remarkable apparent rate heterogeneities through time in
otherwise homogeneous birth-death models of phylogenies. They are a potential …

Since the ignition of the HIV-1 group M pandemic in the beginning of the 20th century, group
M lineages have spread heterogeneously throughout the world. Subtype C spread rapidly …

Modern phylodynamic methods interpret an inferred phylogenetic tree as a partial
transmission chain providing information about the dynamic process of transmission and …