The widespread use of antibiotics has made the problem of bacterial resistance increasingly
serious, and the study of new drug-resistant bacteria has become the main direction of …

Infective diseases have become health threat of a global proportion due to appearance and
spread of microorganisms resistant to majority of therapeutics currently used for their …

Although most of the heterocycles have been reported to possess a significant
pharmacological activity, only a few of them, namely quinoline derivatives, have exhibited …

Antibiotic resistance is one of the most important challenges of the 21st century. However,
the growing understanding of bacterial pathogenesis and cell-to-cell communication has …

Microorganisms participating in the development of biofilms exhibit heightened resistance to
antibiotic treatment, therefore infections involving biofilms have become a problem in recent …

Nosocomial infections are among the major public health concerns, especially during the
ongoing Covid19 pandemic. There is a great demand for novel chemical agents that are …

Antimicrobial activity and post-antibiotic effects (PAEs) are both important parameters in
determination of the dosage regimen of antimicrobial agents. In the present study …

Biofilms, the predominant growth mode of microorganisms, pose a significant risk to human
health. The protective biofilm matrix, typically composed of exopolysaccharides, proteins …

Antimicrobial resistance poses a significant global health threat, necessitating innovative
approaches for combatting it. This review explores various mechanisms of antimicrobial …

Oxazolidinone scaffolds have a significant role in drug discovery and development.
Compounds with an oxazolidinone skeleton have a wide range of pharmacologic effects …