Synergistic effect of chlorogenic acid and vitamin D3 (cholecalciferol) on in-vitro glycation may assist in prevention of Polycystic Ovarian Syndrome (PCOS) …
Advanced glycation end products (AGEs) are formed through non-enzymatic glycation, that
have been linked to various diseases, including polycystic ovarian syndrome (PCOS) …
have been linked to various diseases, including polycystic ovarian syndrome (PCOS) …
Rutin impedes human low-density lipoprotein from non-enzymatic glycation: A mechanistic insight against diabetes-related disorders
Glycation of human low-density protein (LDL) has an essential contribution to cardiovascular
diseases. Natural compounds like rutin have been extensively studied in preventing …
diseases. Natural compounds like rutin have been extensively studied in preventing …
Studies on the interaction of 2, 4-dibromophenol with human hemoglobin using multi-spectroscopic, molecular docking and molecular dynamics techniques
Dibromophenol (DBP) has several industrial applications, including as a wood preservative
and flame retardant. This study investigated the interaction between DBP and human …
and flame retardant. This study investigated the interaction between DBP and human …
Inhibitory Potential of the Ocimum sanctum Phytochemicals on Bruton's Tyrosine Kinase, a Well-Known Drug Target for Treatment of Chronic Lymphocytic Leukemia …
Chronic lymphocytic leukemia (CLL) is an incurable neoplasm of B-lymphocytes, which
accounts for about one-third of all leukemias. Ocimum sanctum, an herbaceous perennial, is …
accounts for about one-third of all leukemias. Ocimum sanctum, an herbaceous perennial, is …
[HTML][HTML] Assessing the ability of Polysaccharides extracted from Date Palm Fruit to salvage Wistar rats from cisplatin-linked hepatic damage
OO Adewale, RF Oyelola, JO Oladele… - … Modern Chinese Medicine, 2024 - Elsevier
Background Cisplatin is a platinum-based chemotherapeutic drug utilized in the treatment of
many solid-tissue cancers; it is associated with several organ toxicities. For ages, Phoenix …
many solid-tissue cancers; it is associated with several organ toxicities. For ages, Phoenix …
A computational odyssey: uncovering classical β-lactamase inhibitors in dry fruits
In the antibacterial arsenal, β-lactams have held a prominent position, but increasing
resistance due to unauthorized use and genetic factors requires new strategies. Combining …
resistance due to unauthorized use and genetic factors requires new strategies. Combining …
Dopamine and Central Dopaminergic Circuitry in Neurodegenerative Diseases: Roles and Mechanisms of Action of Natural Phytochemicals
There has been increasing effort in the research and development of dopamine
neurotransmission as an early clinical marker for neurodegenerative diseases, namely …
neurotransmission as an early clinical marker for neurodegenerative diseases, namely …
[HTML][HTML] Anti-aggregation potential of polyphenols from Ajwa date palm (Phoenix dactylifera): An in-silico analysis
Background Amyloid β (Aβ) fibril agglomeration is crucial in Alzheimer's disease (AD)
etiology, leading to significant harm to the central nervous system. Polyphenols have been …
etiology, leading to significant harm to the central nervous system. Polyphenols have been …
[HTML][HTML] In Silico and In Vitro Studies to Explore the Effect of Thymoquinone on Isocitrate Lyase, Biofilm Formation, and the Expression of Some Virulence Genes in …
Thymoquinone (TQ), a bioactive compound from black cumin (Nigella sativa), has
demonstrated a broad range of therapeutic effects. The aim of this study is to evaluate the …
demonstrated a broad range of therapeutic effects. The aim of this study is to evaluate the …
Photoinduced electron transfer photodecomposition of 1, 4-Dihydropyridine derivative phototoxic drug Manidipine, Docking and Molecular Dynamic studies
The present investigation focuses on the photochemical transformation of Manidipine (1)
using ultraviolet-A light while being accompanied by an electron-donating agent (Et 3 N) …
using ultraviolet-A light while being accompanied by an electron-donating agent (Et 3 N) …