Role of human macrophage polarization in inflammation during infectious diseases
C Atri, FZ Guerfali, D Laouini - International journal of molecular sciences, 2018 - mdpi.com
Experimental models have often been at the origin of immunological paradigms such as the
M1/M2 dichotomy following macrophage polarization. However, this clear dichotomy in …
M1/M2 dichotomy following macrophage polarization. However, this clear dichotomy in …
Tumor associated macrophages: origin, recruitment, phenotypic diversity, and targeting
The tumour microenvironment (TME) is known to have a strong influence on tumourigenesis,
with various components being involved in tumour suppression and tumour growth. A …
with various components being involved in tumour suppression and tumour growth. A …
Cancer cell states recur across tumor types and form specific interactions with the tumor microenvironment
Transcriptional heterogeneity among malignant cells of a tumor has been studied in
individual cancer types and shown to be organized into cancer cell states; however, it …
individual cancer types and shown to be organized into cancer cell states; however, it …
Cellular backpacks for macrophage immunotherapy
Adoptive cell transfers have emerged as a disruptive approach to treat disease in a manner
that is more specific than using small-molecule drugs; however, unlike traditional drugs …
that is more specific than using small-molecule drugs; however, unlike traditional drugs …
Neutrophil-to-Lymphocyte ratio (NLR) and Platelet-to-Lymphocyte ratio (PLR) as prognostic markers in patients with non-small cell lung cancer (NSCLC) treated with …
S Diem, S Schmid, M Krapf, L Flatz, D Born, W Jochum… - Lung cancer, 2017 - Elsevier
Objectives Immunotherapy with the programmed death receptor-1 (PD-1) antibody
nivolumab has changed the field of metastatic non-small cell lung cancer (NSCLC) …
nivolumab has changed the field of metastatic non-small cell lung cancer (NSCLC) …
Tumor‐derived exosomal miR‐19b‐3p facilitates M2 macrophage polarization and exosomal LINC00273 secretion to promote lung adenocarcinoma metastasis via …
J Chen, K Zhang, Y Zhi, Y Wu, B Chen… - Clinical and …, 2021 - Wiley Online Library
Numerous reports have elucidated the important participation of exosomes in the
communication between tumor cells and other cancer‐related cells including tumor …
communication between tumor cells and other cancer‐related cells including tumor …
[PDF][PDF] Macrophage polarization contributes to glioblastoma eradication by combination immunovirotherapy and immune checkpoint blockade
D Saha, RL Martuza, SD Rabkin - Cancer cell, 2017 - cell.com
Glioblastoma is an immunosuppressive, fatal brain cancer that contains glioblastoma stem-
like cells (GSCs). Oncolytic herpes simplex virus (oHSV) selectively replicates in cancer …
like cells (GSCs). Oncolytic herpes simplex virus (oHSV) selectively replicates in cancer …
Lipids in the tumor microenvironment: From cancer progression to treatment
Over the past decade, the study of metabolic abnormalities in cancer cells has risen
dramatically. Cancer cells can thrive in challenging environments, be it the hypoxic and …
dramatically. Cancer cells can thrive in challenging environments, be it the hypoxic and …
Genetic programming of macrophages to perform anti-tumor functions using targeted mRNA nanocarriers
Tumor-associated macrophages (TAMs) usually express an M2 phenotype, which enables
them to perform immunosuppressive and tumor-promoting functions. Reprogramming these …
them to perform immunosuppressive and tumor-promoting functions. Reprogramming these …
Spatial density and distribution of tumor-associated macrophages predict survival in non–small cell lung carcinoma
The respective antitumoral and protumoral roles of M1 and M2 tumor-associated
macrophages (TAM) typify the complexity of macrophage function in cancer. In lung cancer …
macrophages (TAM) typify the complexity of macrophage function in cancer. In lung cancer …